Manipulative Treatment of Myofascial Pain Syndrome: A Network Meta-Analysis Based on Randomized Controlled Trials.

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Journal of Pain Research Pub Date : 2025-04-10 eCollection Date: 2025-01-01 DOI:10.2147/JPR.S517869
Jing Chen, Linyu Yin, Qing Hu, Songtao Liu, Lirong Zeng
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Abstract

Objective: Myofascial pain syndrome (MPS) is a common condition. Manual therapy is preferred over other invasive treatments due to its noninvasiveness and safety, but evidence for its effectiveness is lacking. We here conducted a comprehensive search of randomized controlled trial studies related to manipulative therapy for MPS and conducted a network meta-analysis to provide a basis for clinical applications and experimental studies.

Methods: Reports on randomized controlled trials of noninvasive therapy for MPS deposited in the China National Knowledge Infrastructure database, Chinese Science Citation Database(CSCD), Chinese Citation Database(CCD), Chinese Biomedical Database, PubMed, Embase, Cochrane Library, and Web of Science from their respective inception dates until November 10, 2024, were retrieved. A network meta-analysis was performed using Rv4.2.0 software.

Results: Fourteen studies involving 588 patients overall were included. The interventions included pain point compression, massage, and ischemic compression. Visual analogue scale scores were reported in 12 studies and the pressure pain threshold was reported in five studies. The outcomes demonstrated that manipulation had a notable effect, although not statistically significant, as compared with conventional treatment and placebo. Overall, the effect of pain-point compression was favorable. The results were stable, with no significant publication bias.

Conclusion: Manipulation was an effective treatment for MPS, but the effects were not statistically significant, based on the findings of this study. Owing to issues such as uneven methodological quality and the small sample size of the included studies, further high-quality multicenter, large-sample, randomized double-blind controlled trials are required to verify the reliability of this conclusion.

手法治疗肌筋膜疼痛综合征:基于随机对照试验的网络荟萃分析。
目的:肌筋膜疼痛综合征(MPS)是一种常见的疾病。由于其无创性和安全性,手工治疗优于其他侵入性治疗,但缺乏其有效性的证据。本文对手法治疗MPS相关的随机对照试验研究进行了全面检索,并进行了网络meta分析,为临床应用和实验研究提供依据。方法:检索中国国家知识基础设施数据库、中国科学引文数据库(CSCD)、中国引文数据库(CCD)、中国生物医学数据库、PubMed、Embase、Cochrane图书馆和Web of Science自各自建库日期至2024年11月10日的MPS无创治疗随机对照试验报告。采用Rv4.2.0软件进行网络meta分析。结果:14项研究共纳入588例患者。干预措施包括痛点压迫、按摩和缺血压迫。12项研究报告了视觉模拟量表评分,5项研究报告了压痛阈值。结果表明,与常规治疗和安慰剂相比,操作具有显著的效果,尽管在统计学上不显着。总的来说,疼痛点压缩的效果是良好的。结果是稳定的,没有明显的发表偏倚。结论:手法治疗MPS是一种有效的治疗方法,但根据本研究结果,其效果无统计学意义。由于纳入研究的方法学质量参差不齐、样本量小等问题,需要进一步开展高质量的多中心、大样本、随机双盲对照试验来验证这一结论的可靠性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Pain Research
Journal of Pain Research CLINICAL NEUROLOGY-
CiteScore
4.50
自引率
3.70%
发文量
411
审稿时长
16 weeks
期刊介绍: Journal of Pain Research is an international, peer-reviewed, open access journal that welcomes laboratory and clinical findings in the fields of pain research and the prevention and management of pain. Original research, reviews, symposium reports, hypothesis formation and commentaries are all considered for publication. Additionally, the journal now welcomes the submission of pain-policy-related editorials and commentaries, particularly in regard to ethical, regulatory, forensic, and other legal issues in pain medicine, and to the education of pain practitioners and researchers.
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