Carmen Borrás-Sansaloni, Marina Ricco-Pérez, Antoni Mayol, Capilla Navarro-Guzmán, José Manuel García-Montes, Emilio Lopez-Navarro
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引用次数: 0
Abstract
Background: Psychotic disorders are characterized by both positive symptoms (hallucinations, delusions) and negative symptoms (emotional blunting, anhedonia) that impair daily functioning. While antipsychotic drugs and psychological interventions are effective when addressing positive symptoms, treatment of negative symptoms remains an ongoing challenge. Mindfulness-based interventions (MBIs) have been shown to reduce negative psychotic symptoms. However, as negative psychotic symptoms are assessed as a sole entity rather than a sum of manifestations, the effect of MBIs remains unclear.
Aim: To examine the effects of MBI in addition to integrated rehabilitation treatment (IRT) for people experiencing psychosis on each of the negative psychotic symptoms.
Methods: A randomized controlled clinical trial with preintervention and postintervention measures was designed. The main outcome variable was negative psychotic symptoms assessed through the seven subscales of the Spanish version of the positive and negative syndrome scale. Data were analyzed using a repeated measures analysis of variance and reliable change index calculation.
Results: There were no statistical differences between groups at the preintervention assessment. Statistically significant differences were found after MBI for the time in emotional withdrawal (F = 37.75, P < 0.001, η2 = 0.437) and social withdrawal (F = 37.75, P < 0.001, η2 = 0.437).
Conclusion: MBI added to IRT reduced the lack of interest and involvement with affective commitment to daily life activities, and interest and engagement in social activities increased. These negative psychotic symptoms were not improved by IRT alone.
背景:精神障碍的特点是阳性症状(幻觉、妄想)和阴性症状(情绪迟钝、快感缺乏)都损害日常功能。虽然抗精神病药物和心理干预在处理阳性症状时是有效的,但治疗阴性症状仍然是一个持续的挑战。正念干预(MBIs)已被证明可以减少消极的精神病症状。然而,由于消极的精神症状是作为一个单独的实体而不是表现的总和来评估的,mbi的效果仍然不清楚。目的:探讨MBI加综合康复治疗(IRT)对精神病患者各阴性精神病症状的影响。方法:采用随机对照临床试验设计,包括干预前和干预后措施。主要结果变量是通过西班牙版阳性和阴性综合征量表的七个亚量表评估的阴性精神病症状。数据分析采用重复测量方差分析和可靠的变化指数计算。结果:两组间干预前评估无统计学差异。MBI后情绪戒断(F = 37.75, P < 0.001, η 2 = 0.437)和社交戒断(F = 37.75, P < 0.001, η 2 = 0.437)的时间差异有统计学意义。结论:在IRT中加入MBI减少了对日常生活活动缺乏兴趣和参与的情感承诺,对社会活动的兴趣和参与增加。这些阴性的精神病症状不能通过单独的IRT得到改善。
期刊介绍:
The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.