{"title":"Hybrid Deep Maxout-VGG-16 model for brain tumour detection and classification using MRI images","authors":"T. Loganayagi , Meesala Sravani , Balajee Maram , Telu Venkata Madhusudhana Rao","doi":"10.1016/j.jbiotec.2025.05.009","DOIUrl":null,"url":null,"abstract":"<div><div>Brain tumor detection is essential to identify tumors at an early stage, allowing for more effective treatment. The patient's chances of recovery and survival can be improved by early detection. The existing methods for detecting brain tumour have several limitations, including limited accessibility, exposure to radiation, high costs and potential for false negatives. To overcome the issues, a Deep Maxout-Visual Geometry Group-16 (DM-VGG-16) model is devised for detecting tumour in brain from Magnetic Resonance Imaging (MRI). Initially, MRI image is sent for pre-processing as input. Here, Non-Local Mean (NLM) filter performs pre-processing. The pre-processed image is subjected to segmentation stage, which is accomplished by Template–based K-means and improved Fuzzy C Means algorithm (TKFCM). Moreover, in feature extraction stage, various features, like area, cluster prominence, Hybrid PCA- Normalized GIST (NGIST) and Improved Median binary Pattern (IMBP) are extracted. Lastly, proposed DM-VGG-16 model is utilized for detection of brain tumors from extracted features. The DM-VGG-16 is the integration of Deep Maxout Network (DMN) and Visual Geometry Group-16 (VGG-16). The DM-VGG-16 outperformed superior results than conventional techniques with performance metrics, including accuracy, True Negative Rate (TNR) and True Positive Rate (TPR) of 90.76 %, 90.65 % and 90.75 % correspondingly.</div></div>","PeriodicalId":15153,"journal":{"name":"Journal of biotechnology","volume":"405 ","pages":"Pages 124-138"},"PeriodicalIF":4.1000,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biotechnology","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0168165625001257","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Brain tumor detection is essential to identify tumors at an early stage, allowing for more effective treatment. The patient's chances of recovery and survival can be improved by early detection. The existing methods for detecting brain tumour have several limitations, including limited accessibility, exposure to radiation, high costs and potential for false negatives. To overcome the issues, a Deep Maxout-Visual Geometry Group-16 (DM-VGG-16) model is devised for detecting tumour in brain from Magnetic Resonance Imaging (MRI). Initially, MRI image is sent for pre-processing as input. Here, Non-Local Mean (NLM) filter performs pre-processing. The pre-processed image is subjected to segmentation stage, which is accomplished by Template–based K-means and improved Fuzzy C Means algorithm (TKFCM). Moreover, in feature extraction stage, various features, like area, cluster prominence, Hybrid PCA- Normalized GIST (NGIST) and Improved Median binary Pattern (IMBP) are extracted. Lastly, proposed DM-VGG-16 model is utilized for detection of brain tumors from extracted features. The DM-VGG-16 is the integration of Deep Maxout Network (DMN) and Visual Geometry Group-16 (VGG-16). The DM-VGG-16 outperformed superior results than conventional techniques with performance metrics, including accuracy, True Negative Rate (TNR) and True Positive Rate (TPR) of 90.76 %, 90.65 % and 90.75 % correspondingly.
期刊介绍:
The Journal of Biotechnology has an open access mirror journal, the Journal of Biotechnology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The Journal provides a medium for the rapid publication of both full-length articles and short communications on novel and innovative aspects of biotechnology. The Journal will accept papers ranging from genetic or molecular biological positions to those covering biochemical, chemical or bioprocess engineering aspects as well as computer application of new software concepts, provided that in each case the material is directly relevant to biotechnological systems. Papers presenting information of a multidisciplinary nature that would not be suitable for publication in a journal devoted to a single discipline, are particularly welcome.