The value of MR neurography in assessing lesions of the thoracic dorsal root ganglia in patients with zoster-associated pain.

IF 4.7 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
European Radiology Pub Date : 2025-10-01 Epub Date: 2025-04-16 DOI:10.1007/s00330-025-11575-4
Dejun She, Yalan Yan, Junhuan Hong, Dongmei Jiang, Hao Jiang, Ying Zou, Xiance Zhao, Dairong Cao
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引用次数: 0

Abstract

Objectives: To evaluate the imaging characteristics of the thoracic dorsal root ganglia (DRG) in patients with zoster-associated pain (ZAP) using magnetic resonance neurography (MRN) and its correlation with disease stages and serological marker.

Methods: Twenty-six consecutive ZAP patients with different disease stages (acute herpes neuralgia, subacute herpes neuralgia, and postherpetic neuralgia) and thirteen healthy subjects were scanned on a 3-T MR scanner for thoracic DRG visualization. The T1-T12 DRG for each ZAP patient were divided into three groups (prominent affected segment, rash distribution segment, and non-rash distribution segment). The volume and T2 signal intensity (SI) of thoracic DRG were measured and compared. The visual analog scale (VAS) and serological data were also recorded.

Results: The volume ratio of prominent affected thoracic DRG in ZAP patients was larger than that in non-rash distribution segment of ZAP patients and that in the healthy group, respectively (both p < 0.05). The volume ratio of affected DRG in the acute herpes neuralgia and subacute herpes neuralgia group was both higher than that in the postherpetic neuralgia group (both p < 0.05). For T2 SI, no differences were found among three disease stages. The ESR index was the only parameter associated with volume ratio of prominent affected DRG segment (r = 0.48, p = 0.01).

Conclusion: MRN is able to visualize and identify morphological changes of thoracic DRG of ZAP patients. The imaging characteristics of affected thoracic DRG exhibit differences across different disease stages, which was associated with ESR index in ZAP patients.

Key points: Question Magnetic resonance neurography is able to detect the abnormal imaging features of dorsal root ganglia (DRG) in zoster-associated pain patients. Findings Magnetic resonance neurography (MRN) demonstrates a difference in the volume ratio of affected DRG among three disease stages in zoster-associated pain (ZAP) patients. Clinical relevance Combining serological parameter with observed thoracic DRG volume changes on MRN may serve as a viable predictor for ZAP development.

MR神经造影评估带状疱疹相关疼痛患者胸背根神经节病变的价值。
目的:探讨带状疱疹相关性疼痛(ZAP)患者胸椎背根神经节(DRG)的磁共振神经成像特征及其与疾病分期和血清学标志物的相关性。方法:对26例不同疾病分期(急性疱疹性神经痛、亚急性疱疹性神经痛和带状疱疹后神经痛)的ZAP患者和13名健康者进行3-T MR扫描,观察其胸部DRG的显像。将每位ZAP患者的T1-T12 DRG分为三组(突出受累段、皮疹分布段和非皮疹分布段)。测量并比较胸部DRG的体积和T2信号强度(SI)。同时记录视觉模拟评分(VAS)和血清学数据。结果:ZAP患者胸部突出病变DRG的体积比分别大于ZAP患者非皮疹分布段和健康组(p)。结论:MRN能够可视化和识别ZAP患者胸部DRG的形态学变化。受影响的胸部DRG的影像学特征在不同的疾病阶段表现出差异,这与ZAP患者的ESR指数有关。磁共振神经成像能够检测带状疱疹相关疼痛患者的背根神经节(DRG)异常影像学特征。磁共振神经成像(MRN)显示带状疱疹相关疼痛(ZAP)患者三个疾病阶段受影响DRG的体积比存在差异。将血清学参数与MRN上观察到的胸部DRG体积变化相结合,可以作为ZAP发展的可行预测指标。
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来源期刊
European Radiology
European Radiology 医学-核医学
CiteScore
11.60
自引率
8.50%
发文量
874
审稿时长
2-4 weeks
期刊介绍: European Radiology (ER) continuously updates scientific knowledge in radiology by publication of strong original articles and state-of-the-art reviews written by leading radiologists. A well balanced combination of review articles, original papers, short communications from European radiological congresses and information on society matters makes ER an indispensable source for current information in this field. This is the Journal of the European Society of Radiology, and the official journal of a number of societies. From 2004-2008 supplements to European Radiology were published under its companion, European Radiology Supplements, ISSN 1613-3749.
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