Sangram Keshari Behera, Debahuti Mohapatra, Debirupa De, Krishna Sai Sharan, Swagatika Samal
{"title":"Villiform cardiac myxoma with atypical glandular differentiation in a young girl: a case report.","authors":"Sangram Keshari Behera, Debahuti Mohapatra, Debirupa De, Krishna Sai Sharan, Swagatika Samal","doi":"10.1186/s13256-025-05229-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cardiac myxoma with glandular differentiation is a rare finding. It accounts for approximately ≤ 3% of all cardiac myxomas. The presence of cellular atypia resembling adenocarcinoma is an extremely rare finding in cardiac myxoma.</p><p><strong>Case presentation: </strong>Here, we present a case of villiform cardiac myxoma with atypical glandular differentiation in a 16-year-old Indo-Aryan girl, which was initially mistaken as metastatic adenocarcinoma on routine histology.</p><p><strong>Conclusion: </strong>A thorough histopathological examination, supported by immunohistochemical and radiological correlation, assists in accurate diagnosis and concurrently evades the misdiagnosis of metastatic adenocarcinoma.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"190"},"PeriodicalIF":0.9000,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020086/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13256-025-05229-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Cardiac myxoma with glandular differentiation is a rare finding. It accounts for approximately ≤ 3% of all cardiac myxomas. The presence of cellular atypia resembling adenocarcinoma is an extremely rare finding in cardiac myxoma.
Case presentation: Here, we present a case of villiform cardiac myxoma with atypical glandular differentiation in a 16-year-old Indo-Aryan girl, which was initially mistaken as metastatic adenocarcinoma on routine histology.
Conclusion: A thorough histopathological examination, supported by immunohistochemical and radiological correlation, assists in accurate diagnosis and concurrently evades the misdiagnosis of metastatic adenocarcinoma.
期刊介绍:
JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect