{"title":"Reconstruction of 12-lead ECG: a review of algorithms.","authors":"Ekenedirichukwu N Obianom, G André Ng, Xin Li","doi":"10.3389/fphys.2025.1532284","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This paper aims to review the literature on 12-lead ECG reconstruction, highlight various algorithmic approaches and evaluate their predictive strengths. In addition, it investigates the implications of performing reconstruction in particular ways.</p><p><strong>Methods: </strong>This narrative review analysed 39 works on the reconstruction of 12-lead ECGs, focusing on the algorithms used for reconstruction and the results gotten from using these algorithms.</p><p><strong>Results: </strong>The works analysed featured the use of as little as one lead and as much as four leads for reconstruction of the other leads. Linear and nonlinear (including artificial intelligence) algorithms showed promising performances. Their outputs had correlations of greater than 0.90 depending on how the reconstruction models were built.</p><p><strong>Conclusion: </strong>Three leads are optimal as input predictors for minimal reconstruction errors, but there is no universal algorithm that applies to every reconstruction task. Both linear and nonlinear algorithms can achieve high correlations, and minimal root means square errors. Hence, planned steps are needed when deciding how to manipulate the data and build the models to achieve high accuracies.</p>","PeriodicalId":12477,"journal":{"name":"Frontiers in Physiology","volume":"16 ","pages":"1532284"},"PeriodicalIF":3.2000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061857/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3389/fphys.2025.1532284","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: This paper aims to review the literature on 12-lead ECG reconstruction, highlight various algorithmic approaches and evaluate their predictive strengths. In addition, it investigates the implications of performing reconstruction in particular ways.
Methods: This narrative review analysed 39 works on the reconstruction of 12-lead ECGs, focusing on the algorithms used for reconstruction and the results gotten from using these algorithms.
Results: The works analysed featured the use of as little as one lead and as much as four leads for reconstruction of the other leads. Linear and nonlinear (including artificial intelligence) algorithms showed promising performances. Their outputs had correlations of greater than 0.90 depending on how the reconstruction models were built.
Conclusion: Three leads are optimal as input predictors for minimal reconstruction errors, but there is no universal algorithm that applies to every reconstruction task. Both linear and nonlinear algorithms can achieve high correlations, and minimal root means square errors. Hence, planned steps are needed when deciding how to manipulate the data and build the models to achieve high accuracies.
期刊介绍:
Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.