Non-celiac Enteropathies.

Q1 Medicine

Current Gastroenterology Reports Pub Date : 2025-04-14 DOI:10.1007/s11894-025-00979-3

Kaitlyn Mi, Scarlett Cao, Dawn Adams

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Abstract

Purpose of review: Non-celiac enteropathies (NCE) can be due to a variety of causes. The workup for NCE includes history, physical, laboratory and histology review and can be difficult. Enteropathies can result in serious illness due to consequences of malabsorption including severe weight loss, nutritional deficiencies, and debilitating diarrhea. Recognition and support of these consequences while investigating underlying etiology is essential.

Recent findings: Recent studies in NCEs have focused on improving diagnostic accuracy and predicting long-term outcomes in patients with NCEs. Further, literature has emphasized the importance of histological analysis, with a focus on differentiating between various enteropathies that cause villous atrophy, highlighting the complexity and need for personalized approaches in managing these conditions. Identification of etiologies of NCEs requires review of patients' detailed history, medications, and lab results. Common etiologies include immunodeficiencies, infectious, iatrogenic, and malignant causes. Using a systematic approach can lead to proper diagnosis and tailor treatment choices, benefiting patient outcomes. Supportive nutrition care should be initiated early when applicable to minimize morbidity.

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Non-celiac肠下垂。

综述目的：非乳糜泻性肠病（NCE）可由多种原因引起。NCE的检查包括病史、物理检查、实验室检查和组织学检查，可能比较困难。肠道疾病可导致严重的疾病，由于吸收不良的后果，包括严重的体重减轻，营养缺乏，和虚弱的腹泻。在调查潜在病因的同时，认识和支持这些后果是至关重要的。最近的发现：最近对nce的研究主要集中在提高诊断准确性和预测nce患者的长期预后。此外，文献强调了组织学分析的重要性，重点是区分引起绒毛萎缩的各种肠病，强调了管理这些疾病的复杂性和个性化方法的必要性。nce的病因鉴定需要回顾患者的详细病史、药物和实验室结果。常见的病因包括免疫缺陷、感染、医源性和恶性病因。采用系统的方法可以导致正确的诊断和量身定制的治疗选择，有利于患者的结果。支持性营养护理应尽早开始，以尽量减少发病率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Gastroenterology Reports Medicine-Gastroenterology

CiteScore

7.80

自引率

0.00%

发文量

期刊介绍： As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.