Effect of precooling on the assessment of pain during local anesthesia in adults: A systematic review and meta-analysis.

Q2 Dentistry
Ana Beatriz Leme de Andrade, Sandra Lúcia Dantas de Moraes, Arthur José Barbosa de França, Rayanna Thayse Florêncio Costa, Eduardo Piza Pellizzer, Belmiro Cavalcanti do Egito Vasconcelos
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引用次数: 0

Abstract

Background: Various methods aim to reduce pain from local anesthesia injections. While commonly used, topical anesthetics have limitations. This systematic review aimed to assess whether precooling is a more effective alternative to topical anesthetics for pain control during local anesthesia injections in adults.

Material and methods: The review followed PRISMA guidelines and used the PICO framework. The protocol was registered in PROSPERO (CRD42023446314). Independent searches were conducted in PubMed/MEDLINE, SCOPUS, and Web of Science for studies published up to November 2024. Articles meeting the eligibility criteria were included. Data were extracted by one author and verified by another. A meta-analysis was performed to evaluate pain between the precooling and topical anesthetic groups after anesthesia and during needle insertion.

Results: Eight randomized clinical trials met the inclusion criteria, with a combined sample of 415 patients. Six of the eight studies reported lower pain scores in patients who received precooling compared to those treated with topical anesthetics. Various agents were used for both local cooling and topical anesthesia. Meta-analysis showed statistically significant pain reduction in favor of precooling after anesthesia; however, no significant differences were found during needle insertion.

Conclusions: Precooling may be an effective alternative to topical anesthetics, reducing pain associated with needle insertion and anesthetic injection in adults. Further research is warranted to establish a standardized application protocol. Key words:Local anesthesia, pain, precooling, cryoanesthesia, systematic review.

预冷对成人局部麻醉疼痛评估的影响:一项系统回顾和荟萃分析。
背景:各种方法旨在减轻局麻注射后的疼痛。虽然常用,但局部麻醉剂有局限性。本系统综述旨在评估在成人局部麻醉注射中,预冷是否是一种更有效的替代局部麻醉来控制疼痛的方法。材料和方法:本研究遵循PRISMA指南,采用PICO框架。该协议已在PROSPERO (CRD42023446314)中注册。在PubMed/MEDLINE, SCOPUS和Web of Science中进行了独立搜索,以获取截至2024年11月发表的研究。符合资格标准的文章被纳入。数据由一位作者提取,另一位作者验证。进行了一项荟萃分析来评估麻醉后和插针时预冷组和表面麻醉组之间的疼痛。结果:8项随机临床试验符合纳入标准,共纳入415例患者。八项研究中有六项报告了接受预冷治疗的患者疼痛评分低于接受局部麻醉治疗的患者。局部冷却和表面麻醉均使用多种药物。meta分析显示,麻醉后预冷有利于疼痛减轻;然而,在针头插入时,没有发现显着差异。结论:预冷可能是一种有效的替代表面麻醉剂的方法,可以减少成人针头插入和麻醉剂注射带来的疼痛。需要进一步研究以建立标准化的应用协议。关键词:局麻,疼痛,预冷,低温麻醉,系统评价
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来源期刊
CiteScore
2.70
自引率
0.00%
发文量
118
期刊介绍: Indexed in PUBMED, PubMed Central® (PMC) since 2012 and SCOPUSJournal of Clinical and Experimental Dentistry is an Open Access (free access on-line) - http://www.medicinaoral.com/odo/indice.htm. The aim of the Journal of Clinical and Experimental Dentistry is: - Periodontology - Community and Preventive Dentistry - Esthetic Dentistry - Biomaterials and Bioengineering in Dentistry - Operative Dentistry and Endodontics - Prosthetic Dentistry - Orthodontics - Oral Medicine and Pathology - Odontostomatology for the disabled or special patients - Oral Surgery
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