The Usefulness of ETDQ-7 Score in Assessing ETD

IF 1.5 4区 医学 Q2 OTORHINOLARYNGOLOGY
Niels Højvang Holm, Therese Ovesen
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引用次数: 0

Abstract

Introduction

The ETDQ-7 questionnaire has been validated for diagnosing Eustachian tube dysfunction (ETD) and a minimal clinically important difference (MCID) of > 3.5 has been suggested. We aim to assess the use of ETDQ-7 for assessing ETD and a potential correlation between ETDQ-7 and the Sino-Nasal Outcome Test 22 (SNOT-22).

Methods

ETD was based on relevant ear symptoms and objective signs of negative middle ear pressure in 75 consecutive adult patients. Ventilation tube insertion (VTi) was performed on affected ears. ETDQ-7 and SNOT-22 scores before and 1 month after VTi were compared to 75 healthy controls.

Results

Mean ETDQ-7 score decreased from 31.9 to 15.8 (p < 0.0001), remained stable on unaffected ears, and was 9.6 in controls. MCID was achieved on all affected ears after VTi. A cut-off score of > 14.5 for diagnosing ETD yielded 100% sensitivity and 94.2% specificity for ETDQ-7. Spearman's ρ for total score test–retest was 0.878 (p = 0.000). Cronbach alpha for total score varied from 0.6807 to 0.7266. SNOT-22 and ETDQ-7 were correlated at baseline (0.12, p = 0.012). ETD patients scored significantly higher in the nasal, otologic and sleep domains in SNOT-22 compared to controls.

Conclusion

ETDQ-7 is a very valid tool for ETD diagnostics and assessing the ear-related effects of VTi. ETDQ-7 scores reveal residual symptoms after VTi, indicating symptom relief but no cure for the underlying pathophysiology. For future investigation, we suggest assessing ETDQ-7 scores for each ear separately, higher MCID values, and integration of quality of life measures.

Trial Registration: ClinicalTrials.gov: NCT05055115

Abstract Image

ETDQ-7评分在评估ETD中的作用。
导语:ETDQ-7问卷已被证实可用于诊断咽鼓管功能障碍(ETD),并提示最小临床重要差异(MCID)为>.5。我们的目的是评估ETDQ-7用于评估ETD的使用,以及ETDQ-7与中国鼻结局试验22 (SNOT-22)之间的潜在相关性。方法:对连续75例成人患者的相关耳部症状和中耳负压客观体征进行ETD。对患耳行通气管插入术。与75名健康对照比较VTi前后1个月的ETDQ-7、SNOT-22评分。结果:ETDQ-7的平均评分从31.9降至15.8 (p < 14.5),诊断ETD的灵敏度为100%,特异性为94.2%。总分重测的Spearman ρ为0.878 (p = 0.000)。总分的Cronbach alpha值为0.6807 ~ 0.7266。SNOT-22和ETDQ-7在基线时相关(0.12,p = 0.012)。与对照组相比,ETD患者在鼻部、耳部和睡眠领域的SNOT-22得分明显更高。结论:ETDQ-7是诊断ETD和评估VTi耳部相关影响的有效工具。ETDQ-7评分显示VTi后残留症状,提示症状缓解,但基础病理生理未治愈。对于未来的研究,我们建议分别评估每只耳朵的ETDQ-7评分,提高MCID值,并整合生活质量测量。试验注册:ClinicalTrials.gov: NCT05055115。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Otolaryngology
Clinical Otolaryngology 医学-耳鼻喉科学
CiteScore
4.00
自引率
4.80%
发文量
106
审稿时长
>12 weeks
期刊介绍: Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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