Uveitis in child treated for acute myeloblastic leukemia: Do not overlook poststreptococcal inflammation.

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
European Journal of Ophthalmology Pub Date : 2025-07-01 Epub Date: 2025-04-15 DOI:10.1177/11206721251334164
Philippe Gardeton, Inés Chabbi, Margaux Camuset, Chloé Couret, Baptiste Le Calvez, Audrey Grain
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引用次数: 0

Abstract

IntroductionPoststreptococcal uveitis is among the immune complications following strep infections.Case descriptionA patient treated for acute myeloblastic leukemia presented with febrile neutropenia 22 days after consolidation chemotherapy including cytarabine. Diagnosed with Streptococcus mitis bacteremia, she subsequently presented with uveitis in her right eye, linked to the previous infection through positive anti-streptolysin O and negative microbiological test results. Topical treatment resulted in complete recovery.ConclusionThis unprecedented presentation of post-S. mitis uveitis reveals the potential for misdiagnosis of ocular manifestations after cytarabine treatment. Furthermore, neutropenia and profound lymphopenia should not prevent both the ophthalmologist and the hematologist from considering poststreptococcal immune complications.

急性髓母细胞白血病治疗的儿童葡萄膜炎:不要忽视链球菌后炎症。
链球菌性葡萄膜炎是链球菌感染后的免疫并发症之一。病例描述:一例急性髓母细胞白血病患者在接受含阿糖胞苷巩固化疗22天后出现发热性中性粒细胞减少症。她被诊断为链球菌炎菌血症,随后出现右眼葡萄膜炎,这与之前的感染有关,抗溶血素O呈阳性,微生物检测结果呈阴性。局部治疗完全恢复。这是一种前所未有的后s。葡萄膜炎揭示了阿糖胞苷治疗后眼部表现误诊的可能性。此外,中性粒细胞减少症和深度淋巴细胞减少症不应阻止眼科医生和血液科医生考虑链球菌感染后免疫并发症。
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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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