Philippe Gardeton, Inés Chabbi, Margaux Camuset, Chloé Couret, Baptiste Le Calvez, Audrey Grain
{"title":"Uveitis in child treated for acute myeloblastic leukemia: Do not overlook poststreptococcal inflammation.","authors":"Philippe Gardeton, Inés Chabbi, Margaux Camuset, Chloé Couret, Baptiste Le Calvez, Audrey Grain","doi":"10.1177/11206721251334164","DOIUrl":null,"url":null,"abstract":"<p><p>IntroductionPoststreptococcal uveitis is among the immune complications following strep infections.Case descriptionA patient treated for acute myeloblastic leukemia presented with febrile neutropenia 22 days after consolidation chemotherapy including cytarabine. Diagnosed with <i>Streptococcus mitis</i> bacteremia, she subsequently presented with uveitis in her right eye, linked to the previous infection through positive anti-streptolysin O and negative microbiological test results. Topical treatment resulted in complete recovery.ConclusionThis unprecedented presentation of post-<i>S. mitis</i> uveitis reveals the potential for misdiagnosis of ocular manifestations after cytarabine treatment. Furthermore, neutropenia and profound lymphopenia should not prevent both the ophthalmologist and the hematologist from considering poststreptococcal immune complications.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"NP58-NP61"},"PeriodicalIF":1.4000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/11206721251334164","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/15 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
IntroductionPoststreptococcal uveitis is among the immune complications following strep infections.Case descriptionA patient treated for acute myeloblastic leukemia presented with febrile neutropenia 22 days after consolidation chemotherapy including cytarabine. Diagnosed with Streptococcus mitis bacteremia, she subsequently presented with uveitis in her right eye, linked to the previous infection through positive anti-streptolysin O and negative microbiological test results. Topical treatment resulted in complete recovery.ConclusionThis unprecedented presentation of post-S. mitis uveitis reveals the potential for misdiagnosis of ocular manifestations after cytarabine treatment. Furthermore, neutropenia and profound lymphopenia should not prevent both the ophthalmologist and the hematologist from considering poststreptococcal immune complications.
期刊介绍：
The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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