Investigation of Influenza A(H5N1) Virus Neutralization by Quadrivalent Seasonal Vaccines, United Kingdom, 2021–2024

IF 7.2 2区医学 Q1 IMMUNOLOGY

Emerging Infectious Diseases Pub Date : 2025-05-14 DOI:10.3201/eid3106.241796

Phoebe Stevenson-Leggett, Lorin Adams, David Greenwood, Abi Lofts, Vincenzo Libri, Bryan Williams, Sonia Gandhi, Charles Swanton, Steve Gamblin, Edward J. Carr, Ruth Harvey, Nicola S. Lewis, Mary Y. Wu, Emma C. Wall

引用次数: 0

Abstract

We tested cross-neutralization against highly pathogenic avian influenza A(H5N1) virus in adults vaccinated with 2021–2023 seasonal quadrivalent influenza vaccine in the United Kingdom. Seasonal quadrivalent influenza vaccines are unlikely to protect vulnerable persons against severe H5N1 disease during widespread transmission. Enhanced measures are needed to protect vulnerable people from H5N1 virus infection.

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英国2021-2024年四价季节性疫苗中和甲型H5N1流感病毒的调查

我们在英国测试了接种2021-2023年季节性四价流感疫苗的成人对高致病性甲型H5N1禽流感病毒的交叉中和作用。季节性四价流感疫苗不太可能在广泛传播期间保护易感人群免受严重H5N1疾病的侵害。需要加强措施，保护易感人群免受H5N1病毒感染。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Emerging Infectious Diseases 医学-传染病学

CiteScore

17.30

自引率

1.70%

发文量

505

审稿时长

1 months

期刊介绍： Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.