Tunahan Ates, Nebil Akdogan, Ismail Onder Yılmaz, Mehmet Gurkan Arıkan, Mutlu Deger
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引用次数: 0
Abstract
Background: To systematically assess the effectiveness and safety of retrograde intrarenal surgery (RIRS) versus percutaneous nephrolithotomy (PCNL) in treating lower pole stones.
Methods: PubMed, Ovid MEDLINE, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were researched to identify relevant studies up to May 2018. Based on keyword searches, we explored 1972 studies; following screening and eligibility evaluation, 414 studies were removed for various reasons, including 11 possibly relevant studies for this systematic review. A total of 1342 patient data were interpreted (PCNLn = 688; RIRS n = 654).
Results: The stone-free rate (SFR) in ten studies following the PCNL operation varies from 68 to 98.3%, while after the RIRS procedure, it ranges from around 46-93.7%. Out of 10 investigations, 7 demonstrated a superior SFR for the PCNL technique compared to the RIRS. Of the ten investigations, eight demonstrated reduced surgical durations using the PCNL method compared to the RIRS procedure. The duration of hospital stays for the PCNL treatment varies from around 0.3 ± 0.04 to 5.3 ± 1.20 days, while the duration for RIRS procedures ranges from 0 to 3.2 ± 0.52 days. All nine trials indicated a reduced period of hospital stay with the RIRS technique compared to the PCNL procedure. The complication rates in 10 studies following the PCNL surgery varied from approximately 2-72%, while those after the RIRS procedure ranged from about 4-21.6%. Out of 10 trials, 6 demonstrated a reduced complication rate with the RIRS technique compared to the PCNL.
Conclusion: The majority of studies in this systematic review indicate that the PCNL method exhibits a superior SFR, reduced operational duration, prolonged hospital stay, and increased complication rates compared to the RIRS procedure.
Clinical trial number: Not applicable, as this is a systematic review.
背景:系统评估逆行肾内手术(RIRS)与经皮肾镜取石术(PCNL)治疗下极结石的有效性和安全性。方法:检索PubMed、Ovid MEDLINE、Web of Science、Cochrane Central Register of Controlled Trials (Central)和EMBASE,检索截至2018年5月的相关研究。基于关键词搜索,我们探索了1972项研究;在筛选和资格评估后,414项研究因各种原因被删除,其中包括11项可能与本系统评价相关的研究。共有1342例患者数据被解释(PCNLn = 688;RIRS n = 654)。结果:10例PCNL术后无结石率(SFR)为68% ~ 98.3%,而RIRS术后无结石率为46% ~ 93.7%。在10项调查中,7项显示PCNL技术的SFR优于RIRS。在10项调查中,8项显示与RIRS手术相比,使用PCNL方法缩短了手术时间。PCNL治疗的住院时间从0.3±0.04到5.3±1.20天不等,而RIRS治疗的住院时间从0到3.2±0.52天不等。所有9项试验均表明,与PCNL手术相比,RIRS技术可缩短住院时间。在10项研究中,PCNL手术后的并发症发生率约为2-72%,而RIRS手术后的并发症发生率约为4-21.6%。在10项试验中,6项试验显示与PCNL相比,RIRS技术的并发症发生率降低。结论:本系统综述中的大多数研究表明,与RIRS相比,PCNL方法具有更好的SFR、更短的手术时间、更长的住院时间和更高的并发症发生率。临床试验号:不适用,因为这是一项系统评价。
期刊介绍:
BMC Urology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of urological disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
The journal considers manuscripts in the following broad subject-specific sections of urology:
Endourology and technology
Epidemiology and health outcomes
Pediatric urology
Pre-clinical and basic research
Reconstructive urology
Sexual function and fertility
Urological imaging
Urological oncology
Voiding dysfunction
Case reports.