A Randomized Trial Comparing Ultrasound Guided Modified Pectoral Block Versus Erector Spinae Block for Post Mastectomy Pain Management: A Comparative Analysis.

IF 2.9 3区 医学 Q2 ONCOLOGY
Annet Susan Abraham, Punit Mehta, Gautam Girotra, Neeraj Yadav
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Abstract

Background: The modified pectoral nerve (PECS) block is an established technique for providing surgical anesthesia and postoperative analgesia during breast surgery. The erector spinae plane block (ESP), has also been demonstrated to provide extensive multidermatomal sensory block. Our study compared the efficacy and safety of both these USG guided blocks for postoperative analgesia after Modified Radical Mastectomy (MRM).

Methods: 80 adult female patients (ASA grades I and II) undergoing MRM were randomly allocated into 2 groups. Group P received modified PECS block, whereas group E received ESP block using same volume and concentration of 0.375% levobupivacaine (30 mL) after induction of anaesthesia. Fentanyl was used for postoperative pain relief via patient-controlled analgesia (PCA) pumps which was set with fentanyl boluses of 25 mcg, time out interval at 15 minutes and no basal infusion.

Results: The quality of analgesia was significantly better in patients receiving modified PECS block compared with ESP block. Total fentanyl consumed at the end of 24 hrs was significantly lesser in group P (160.85 ± 50.6 mcg) as compared to group E. (235.37 ± 88.42 mcg) (p < .001). At 24 hours postoperatively, mean NRS scores in group P were significantly lower than group E (1.18 ± 1.13 vs. 2.65 ± 0.98) (p < .001). Patients who received modified PECS block had better pain relief and sleep at night compared to group E (p < .001) which was assessed via a Likert scale questionnaire. Interestingly enough, the ease of both abduction and adduction of arm was found to be significantly better in group E as compared to group P at 12 hours (p = .001) and 24 hours (p = .005) postoperatively.

Conclusions: We found that while the modified PECS block offered better postoperative pain relief, the ESP block facilitated physiotherapy, although this advantage was achieved at the cost of less effective pain management. Both blocks showed no adverse effects.

一项比较超声引导改良胸肌阻滞与竖肌阻滞对乳房切除术后疼痛管理的随机试验:比较分析。
背景:改良胸神经阻滞(PECS)是一种成熟的技术,可在乳房手术中提供手术麻醉和术后镇痛。竖脊平面阻滞(ESP)也被证明可以提供广泛的多皮节感觉阻滞。我们的研究比较了两种USG引导阻滞用于改良根治性乳房切除术(MRM)术后镇痛的疗效和安全性。方法:80例ASA分级为I级和II级的成年女性行磁共振成像患者随机分为2组。P组麻醉诱导后给予改良PECS阻滞,E组麻醉诱导后给予同等体积浓度0.375%左布比卡因(30 mL)的ESP阻滞。芬太尼通过患者自控镇痛(PCA)泵缓解术后疼痛,该泵设置芬太尼丸25 mcg,暂停时间为15分钟,无基础输注。结果:改良PECS阻滞组镇痛质量明显优于ESP阻滞组。24 h末芬太尼总消耗量P组(160.85±50.6 mcg)显著低于e组(235.37±88.42 mcg) (P < 0.001)。术后24 h, P组NRS平均评分显著低于E组(1.18±1.13∶2.65±0.98)(P < 0.001)。通过李克特量表问卷评估,与E组相比,接受改良PECS阻滞的患者有更好的疼痛缓解和夜间睡眠(p < 0.001)。有趣的是,在术后12小时(P = 0.001)和24小时(P = 0.005), E组的手臂外展和内收的容易程度明显优于P组。结论:我们发现改良后的PECS阻滞能更好地缓解术后疼痛,而ESP阻滞促进了物理治疗,尽管这一优势是以疼痛管理效果较差为代价的。两种药物均无不良反应。
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来源期刊
Clinical breast cancer
Clinical breast cancer 医学-肿瘤学
CiteScore
5.40
自引率
3.20%
发文量
174
审稿时长
48 days
期刊介绍: Clinical Breast Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of breast cancer. Clinical Breast Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of breast cancer. The main emphasis is on recent scientific developments in all areas related to breast cancer. Specific areas of interest include clinical research reports from various therapeutic modalities, cancer genetics, drug sensitivity and resistance, novel imaging, tumor genomics, biomarkers, and chemoprevention strategies.
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