Viral Entry.

3区医学 Q2 Medicine

Current topics in microbiology and immunology Pub Date : 2025-05-15 DOI:10.1007/82_2025_300

Samantha Hardy, Crystal B Chhan, Amelia R Davis, Andrew T McGuire

引用次数: 0

Abstract

Epstein-Barr virus chiefly infects B cells and epithelial cells but is capable of infecting other cell types in the human host. Host cell entry is a complex process mediated by several viral glycoproteins that define tropism and mediate membrane fusion. This chapter will review what is known about the function of viral glycoproteins in the entry process, explore the nature of interactions between viral glycoproteins and host cell receptors, and highlight gaps in knowledge about the entry process that remain to be filled.

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病毒进入。

爱泼斯坦-巴尔病毒主要感染B细胞和上皮细胞，但也能感染人类宿主体内的其他细胞类型。宿主细胞进入是一个复杂的过程，由几种病毒糖蛋白介导，这些糖蛋白定义趋向性并介导膜融合。本章将回顾已知的病毒糖蛋白在进入过程中的功能，探索病毒糖蛋白与宿主细胞受体之间相互作用的本质，并强调关于进入过程的知识空白仍有待填补。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current topics in microbiology and immunology 医学-免疫学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The review series Current Topics in Microbiology and Immunology provides a synthesis of the latest research findings in the areas of molecular immunology, bacteriology and virology. Each timely volume contains a wealth of information on the featured subject. This review series is designed to provide access to up-to-date, often previously unpublished information.