Effectiveness of aerobic exercise training in patients with obstructive sleep apnea: a systematic review and meta-analysis.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-05-06 DOI:10.1007/s00405-025-09436-3

Mrudula Pawar, Prem Venkatesan, Satyanarayana Mysore, Guruprasad Bhat

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引用次数: 0

Abstract

Purpose: Obstructive sleep apnea (OSA), a sleep-related disorder, reports significant clinical consequences, apart from its socioeconomic burden globally. Among the physiotherapeutic treatment options, exercise training is primarily preferred for these patients. In the current systematic review and meta-analysis, we hypothesize that aerobic exercise training could be beneficial in reducing the severity of OSA.

Methods: A thorough literature search was carried out from Scopus, PubMed, CINAHL, Cochrane, and Embase databases following the PRISMA guidelines, and eight studies were included. The primary outcome was the apnea hypopnea index (AHI) and secondary outcomes were maximal oxygen consumption, oxygen desaturation index, mean oxygen saturation during sleep, Epworth sleepiness scale, body mass index, and neck circumference. RevMan version 5.4.1 was utilized for analysis.

Results: Meta-analysis involved seven studies that showed that aerobic training significantly improved the AHI with a mean difference of -5.24 and an overall effect of p < 0.00001; and VO_2max with a mean difference of 5.84 and an overall effect of p = 0.03. The other secondary outcomes reported improvement but were not significant.

Conclusion: The current review concludes that there is supporting evidence for the beneficial effects of aerobic exercise training in reducing the severity of obstructive sleep apnea.

Prospero registration: CRD42023453316.

查看原文本刊更多论文

有氧运动训练对阻塞性睡眠呼吸暂停患者的有效性：系统回顾和荟萃分析。

目的：阻塞性睡眠呼吸暂停（OSA）是一种与睡眠相关的疾病，除了在全球范围内造成社会经济负担外，还报告了显著的临床后果。在理疗治疗方案中，运动训练是这些患者的首选。在当前的系统回顾和荟萃分析中，我们假设有氧运动训练可能有助于降低OSA的严重程度。方法：按照PRISMA指南对Scopus、PubMed、CINAHL、Cochrane、Embase等数据库进行全面的文献检索，共纳入8篇研究。主要终点是呼吸暂停低通气指数（AHI），次要终点是最大耗氧量、氧去饱和指数、睡眠期间平均血氧饱和度、Epworth嗜睡量表、体重指数和颈围。使用RevMan 5.4.1版本进行分析。结果：meta分析涉及7项研究，结果显示有氧训练显著改善AHI，平均差值为-5.24，总体效果为p2max，平均差值为5.84，总体效果为p = 0.03。其他次要结果报告有改善，但不显著。结论：目前的综述得出结论，有证据支持有氧运动训练对降低阻塞性睡眠呼吸暂停的严重程度有益。普洛斯彼罗注册：CRD42023453316。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.