Cost and availability of high-dose oral prednisone for management of optic neuritis.

IF 3.3 4区 医学 Q1 OPHTHALMOLOGY
Afreen Ahmad, Jonathan A Micieli
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引用次数: 0

Abstract

Objective: This study assesses the cost and availability of 1250 mg of oral prednisone for treatment of optic neuritis across pharmacies in Toronto.

Design: Prospective cross-sectional study PARTICIPANTS: Data collected from 70 pharmacies, across 4 regions in Toronto, Ontario, Canada METHODS: Data were collected from 70 pharmacies on cost and availability for 3- and 5-day courses of prednisone. Pharmacist hesitancy was assessed on the basis of the readiness of the pharmacist to dispense the required dose of medication.

Results: The average cost for a 3-day course of prednisone was $29.10 CAD, and for a 5-day course was $40.40 CAD. Availability was lowest in independent pharmacies (23.8%) and highest in chain pharmacies (47.6%). Although no significant association between availability and pharmacy type was found (χ2 [1; N = 63] = 3.66; p = 0.06), the direction of the effect still shows an indication of chain pharmacies having higher stock. Chain pharmacies also exhibited the highest cost variability. Finally, 40% of pharmacists had some hesitancy or refused to dispense the appropriate dose.

Conclusions: There is limited availability of high-dose prednisone across Toronto, with chain pharmacies offering the highest availability but at a higher cost. There is significant hesitancy about dispensing this prednisone dose among pharmacists. Clinicians should be aware of these trends when prescribing medication for optic neuritis. Neuro-ophthalmologists should aim to develop relationships with pharmacies to improve timely administration of this medication.

大剂量口服强的松治疗视神经炎的成本和可得性。
目的:本研究评估了多伦多各药店治疗视神经炎的1250mg口服强的松的成本和可得性。设计:前瞻性横断面研究参与者:来自加拿大安大略省多伦多市4个地区的70家药店的数据。方法:从70家药店收集3天和5天泼尼松疗程的成本和可得性数据。药剂师的犹豫是在药剂师准备分配所需剂量的药物的基础上进行评估。结果:3天强的松疗程的平均费用为29.10加元,5天疗程的平均费用为40.40加元。可获得性在独立药店最低(23.8%),在连锁药店最高(47.6%)。可获得性与药房类型无显著相关性(χ2 [1;N = 63] = 3.66;P = 0.06),效应方向仍显示连锁药店库存较高。连锁药店也表现出最高的成本变异性。最后,40%的药剂师有一些犹豫或拒绝分配适当的剂量。结论:大剂量强的松在多伦多的可得性有限,连锁药店的可得性最高,但价格较高。在药剂师中,对于分配这种泼尼松剂量有明显的犹豫。临床医生在为视神经炎开药时应注意这些趋势。神经眼科医生应致力于发展与药店的关系,以提高及时管理这种药物。
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来源期刊
CiteScore
3.20
自引率
4.80%
发文量
223
审稿时长
38 days
期刊介绍: Official journal of the Canadian Ophthalmological Society. The Canadian Journal of Ophthalmology (CJO) is the official journal of the Canadian Ophthalmological Society and is committed to timely publication of original, peer-reviewed ophthalmology and vision science articles.
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