Black phosphorus enabled non-invasive protein detection with electromagnetic induction well terahertz biosensor chips.

Abstract

Terahertz biosensors are employed to detect proteins in cancer cells to facilitate early diagnosis and monitoring of cancer treatments. By optimizing the design and functionality of black phosphorus-based sensors, it is possible to enhance their sensitivity and specificity for specific cancer biomarkers, leading to more accurate diagnostic outcomes. The application of the externally applied magnetic field and the 455 nm continuous-wave laser further augments the sensitivity of cellular responses to THz waves, with magnetic influences typically surpassing those of light fields by 10%-80%. Our results examine the photonic properties of black phosphorus, improve its interaction with terahertz waves, and create prototypes that can selectively identify proteins associated with cancer cells. Additionally, the stability and reproducibility of these sensors have been greatly improved, boosting their potential for widespread use in clinical environments.