The Neuroimmune Axis in Gastrointestinal Disorders - An Underrecognized Problem.

Q1 Medicine

Current Gastroenterology Reports Pub Date : 2025-04-15 DOI:10.1007/s11894-025-00973-9

Laura A Pace, Niwen Kong, Mohamed I Itani, James Hemp

引用次数: 0

Abstract

Purpose of review: We present an introduction to the neuroimmune axis with a focus on the gastrointestinal system, its role in numerous chronic multisystem disorders, and emerging tools and therapies to diagnose and treat these conditions.

Recent findings: There have recently been tremendous breakthroughs in our understanding of how the nervous, immune, and endocrine systems, as well as the extracellular matrix and microbiota, interact within the gastrointestinal system to modulate health and disease.

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胃肠道疾病中的神经免疫轴——一个未被认识的问题。

综述目的：我们介绍了神经免疫轴，重点是胃肠道系统，它在许多慢性多系统疾病中的作用，以及诊断和治疗这些疾病的新兴工具和疗法。最近的发现：我们对神经系统、免疫系统和内分泌系统以及细胞外基质和微生物群如何在胃肠道系统内相互作用以调节健康和疾病的理解最近有了巨大的突破。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Gastroenterology Reports Medicine-Gastroenterology

CiteScore

7.80

自引率

0.00%

发文量

期刊介绍： As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.