Investigating Oropouche as a Possible Etiology for Febrile Illness in a Clinical Cohort from Colombia, 2014-2015.

IF 1.9 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Christine S Walsh, Jenny C Cardenas, Lady Y Gutierréz-Silva, Maria U González, Christopher N Mores, Berlin Londono-Renteria, Rebecca C Christofferson
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引用次数: 0

Abstract

Oropouche virus (OROV) is spreading in Latin America and the Caribbean, with travel-associated cases reported in Europe and the United States. There have been more than 8,000 cases in Brazil, including two deaths and an association with late-term stillbirth. Oropouche virus was first detected in Colombia in 2017; however, we aimed to determine if OROV was circulating in Colombia earlier than previously established. We screened 631 serum samples from a hospital cohort collected in 2014-2015 from Cúcuta, Los Patios, and Ocaña. We found evidence of acute OROV infection in three patients from Ocaña. These data suggest that OROV circulated in Colombia earlier than previously detected. With the emergence and expansion of new or neglected viruses, there is a need to expand screening of febrile patients both retroactively and prospectively to describe and better understand the distribution of arbovirus circulation in human populations.

调查2014-2015年哥伦比亚临床队列中Oropouche作为发热性疾病的可能病因
Oropouche病毒(OROV)正在拉丁美洲和加勒比地区传播,欧洲和美国报告了与旅行有关的病例。巴西已有8000多例病例,包括两例死亡和与晚期死产有关。Oropouche病毒于2017年首次在哥伦比亚被发现;然而,我们的目的是确定OROV是否比先前确定的更早在哥伦比亚传播。我们从Cúcuta、Los Patios和Ocaña收集的2014-2015年医院队列中筛选了631份血清样本。我们在Ocaña的3例患者中发现急性OROV感染的证据。这些数据表明,OROV病毒在哥伦比亚传播的时间比以前发现的要早。随着新病毒或被忽视病毒的出现和扩大,有必要扩大对发热患者的回顾性和前瞻性筛查,以描述和更好地了解虫媒病毒在人群中的传播。
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来源期刊
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene 医学-公共卫生、环境卫生与职业卫生
CiteScore
6.20
自引率
3.00%
发文量
508
审稿时长
3 months
期刊介绍: The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine. The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development. The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal. Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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