Long-Term Follow-up of Cytomegalovirus Retinitis in an Immunocompetent Patient.

IF 0.5 Q4 OPHTHALMOLOGY
Michael J Maywood, Lisa J Faia, Tedi Begaj
{"title":"Long-Term Follow-up of Cytomegalovirus Retinitis in an Immunocompetent Patient.","authors":"Michael J Maywood, Lisa J Faia, Tedi Begaj","doi":"10.1177/24741264251338042","DOIUrl":null,"url":null,"abstract":"<p><p><b>Purpose:</b> To describe the long-term follow-up of an immunocompetent patient with cytomegalovirus (CMV) retinitis. <b>Methods:</b> A single case was analyzed and a literature review performed. <b>Results:</b> A 47-year-old woman presented with a paracentral scotoma in the left eye. Examination showed parafoveal retinitis. An aqueous fluid tap was positive for CMV on polymerase chain reaction; however, there was no recent surgery or local or systemic immunosuppression. A thorough workup, including pan imaging, was unremarkable. The retinitis resolved with oral valganciclovir and adjuvant intravitreal ganciclovir and foscarnet injections. At the 3-year follow-up, the patient's disease was inactive without development of systemic illness. <b>Conclusions:</b> In patients presenting with retinitis, the diagnostic use of aqueous polymerase chain reaction is critical, especially in atypical cases in which the retinitis might be associated with CMV.</p>","PeriodicalId":17919,"journal":{"name":"Journal of VitreoRetinal Diseases","volume":" ","pages":"24741264251338042"},"PeriodicalIF":0.5000,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049361/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of VitreoRetinal Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/24741264251338042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: To describe the long-term follow-up of an immunocompetent patient with cytomegalovirus (CMV) retinitis. Methods: A single case was analyzed and a literature review performed. Results: A 47-year-old woman presented with a paracentral scotoma in the left eye. Examination showed parafoveal retinitis. An aqueous fluid tap was positive for CMV on polymerase chain reaction; however, there was no recent surgery or local or systemic immunosuppression. A thorough workup, including pan imaging, was unremarkable. The retinitis resolved with oral valganciclovir and adjuvant intravitreal ganciclovir and foscarnet injections. At the 3-year follow-up, the patient's disease was inactive without development of systemic illness. Conclusions: In patients presenting with retinitis, the diagnostic use of aqueous polymerase chain reaction is critical, especially in atypical cases in which the retinitis might be associated with CMV.

免疫功能正常患者巨细胞病毒性视网膜炎的长期随访。
目的:描述免疫功能正常的巨细胞病毒(CMV)视网膜炎患者的长期随访。方法:对1例病例进行分析,并进行文献复习。结果:一位47岁的女性在左眼出现了一个中央旁暗斑。检查显示视网膜中央凹旁炎。水流式抽头CMV聚合酶链反应阳性;然而,近期没有手术或局部或全身免疫抑制。彻底的检查,包括平移成像,没有什么特别的。通过口服缬更昔洛韦和辅助玻璃体内注射更昔洛韦和氟膦酸钠,视网膜炎得以缓解。在3年的随访中,患者的疾病不活跃,未发生全身性疾病。结论:在患有视网膜炎的患者中,水性聚合酶链反应的诊断是至关重要的,特别是在视网膜炎可能与巨细胞病毒相关的非典型病例中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.20
自引率
16.70%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信