Palliative care with negative pressure wound therapy application in malignant wounds: a systematic review.

IF 1.5 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2025-04-02 DOI:10.12968/jowc.2021.0254

Xiao-Feng Yao, Yen-Jen Wang, Yang-Sheng Lin

{"title":"Palliative care with negative pressure wound therapy application in malignant wounds: a systematic review.","authors":"Xiao-Feng Yao, Yen-Jen Wang, Yang-Sheng Lin","doi":"10.12968/jowc.2021.0254","DOIUrl":null,"url":null,"abstract":"Objective: To synthesise and appraise the evidence for and benefits of palliative application of negative pressure wound therapy (NPWT) in malignant wounds.Method: We performed a systematic review according to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). MEDLINE, Embase, Cochrane Library and trial registers (www.clinicaltrials.gov) from inception to 1 June 2021 were searched. Quality was assessed using the tool of methodological quality and synthesis from the 2018 BMJ Evidence-Based Medicine article on case series and case report synthesis.Results: Of 765 articles screened, 14 eligible studies were included in the review. All were case reports and included a total of 22 patients. The mean age of the patients was 60.7 (range: 33-77) years. The location of the hard-to-heal wounds was widely distributed: five wounds on the scalp; three wounds over the anogenital area; and the remaining wounds on the trunk and extremities. The reported outcomes included: improvement of wound healing; decreased exudation and malodour of the wound; decreased pain sensation; eligibility for further treatment; and a shift to the homecare system.Conclusion: The findings of this study suggested NPWT could be a choice in palliative care for patients with malignant wounds. However, more studies are needed to evaluate the efficacy of NPWT in these wounds.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 4","pages":"304-311"},"PeriodicalIF":1.5000,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of wound care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12968/jowc.2021.0254","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To synthesise and appraise the evidence for and benefits of palliative application of negative pressure wound therapy (NPWT) in malignant wounds.

Method: We performed a systematic review according to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). MEDLINE, Embase, Cochrane Library and trial registers (www.clinicaltrials.gov) from inception to 1 June 2021 were searched. Quality was assessed using the tool of methodological quality and synthesis from the 2018 BMJ Evidence-Based Medicine article on case series and case report synthesis.

Results: Of 765 articles screened, 14 eligible studies were included in the review. All were case reports and included a total of 22 patients. The mean age of the patients was 60.7 (range: 33-77) years. The location of the hard-to-heal wounds was widely distributed: five wounds on the scalp; three wounds over the anogenital area; and the remaining wounds on the trunk and extremities. The reported outcomes included: improvement of wound healing; decreased exudation and malodour of the wound; decreased pain sensation; eligibility for further treatment; and a shift to the homecare system.

Conclusion: The findings of this study suggested NPWT could be a choice in palliative care for patients with malignant wounds. However, more studies are needed to evaluate the efficacy of NPWT in these wounds.

查看原文本刊更多论文

姑息治疗负压伤口治疗在恶性伤口中的应用：系统综述。

目的：综合评价负压创面治疗在恶性创面姑息性应用的证据和疗效。方法：我们根据系统评价和荟萃分析的首选报告项目（PRISMA）进行了系统评价。检索了从成立到2021年6月1日的MEDLINE、Embase、Cochrane Library和试验登记册（www.clinicaltrials.gov）。采用2018年BMJ循证医学文章中关于病例系列和病例报告综合的方法学质量和综合工具对质量进行评估。结果：在筛选的765篇文章中，14篇符合条件的研究纳入了综述。所有病例均为病例报告，共包括22例患者。患者平均年龄60.7岁（33-77岁）。难愈合创面分布广泛：头皮创面5处；肛门生殖器部位有三处伤口；躯干和四肢上的伤口。报道的结果包括：伤口愈合改善；伤口渗出物及恶臭减少；痛觉减少；接受进一步治疗的资格；以及向家庭护理系统的转变。结论：NPWT可作为恶性创伤患者姑息治疗的一种选择。然而，需要更多的研究来评估NPWT在这些伤口中的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.