Trends in obesity-related ischemic heart disease mortality among adults in the United States from 1999 to 2020.

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Future cardiology Pub Date : 2025-04-21 DOI:10.1080/14796678.2025.2490397

Muhammad Umer Sohail, Eliza Aisha, Saad Ahmed Waqas, Muhammad Saad, Muhammad Sameer Arshad, Aymen Ahmed, Muhammad Ovais Sohail, Zara Naveed, Emaan Amin, Sahej Arora, Hafsa Jawaid, Aakriti Jain, Muhammad Mustafa Memon

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引用次数: 0

Abstract

Background: Obesity is a critical risk factor for ischemic heart disease (IHD), affecting 42% of the U.S. population. This study examines trends in obesity-related IHD mortality among U.S. adults aged 25 and older from 1999 to 2020, using the CDC WONDER database.

Research design and methods: We analyzed IHD as the primary cause and obesity as a contributing factor, calculating age-adjusted (AAMRs) and crude mortality rates (CMRs) per 100,000 individuals. Joinpoint regression assessed annual percent changes (APC), stratifying by race, sex, age, and region.

Results: From 1999 to 2020, 139,644 obesity-related IHD deaths were recorded. AAMR rose from 1.92 to 4.69 per 100,000. Rates were higher in men (3.79) than women (2.10), with Black Americans showing the highest AAMR (4.07). Older adults (65+) had the highest CMR (5.73). Nonmetropolitan areas exhibited higher AAMRs (3.47) than metropolitan regions (2.78). States with the highest mortality included Vermont, Oklahoma, Wyoming, Wisconsin and Iowa while Alabama, Virginia, Massachusetts, Connecticut and Georgia had the lowest.

Conclusion: The findings indicate a 2.5-fold increase in obesity-related IHD mortality, highlighting the need for targeted public health interventions and further research to address this growing public health concern.

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1999年至2020年美国成人肥胖相关缺血性心脏病死亡率趋势

背景：肥胖是缺血性心脏病（IHD）的关键危险因素，影响42%的美国人口。本研究使用CDC WONDER数据库，调查了1999年至2020年美国25岁及以上成年人中与肥胖相关的IHD死亡率趋势。研究设计和方法：我们分析了IHD是主要原因，肥胖是一个促成因素，计算了每10万人的年龄调整死亡率（AAMRs）和粗死亡率（CMRs）。联合点回归评估年度百分比变化（APC），按种族、性别、年龄和地区分层。结果：从1999年到2020年，记录了139,644例与肥胖相关的IHD死亡。AAMR从每10万人1.92人上升到4.69人。男性的AAMR（3.79）高于女性（2.10），其中黑人的AAMR最高（4.07）。老年人（65岁以上）的CMR最高（5.73）。非首都地区的aamr（3.47）高于首都地区（2.78）。死亡率最高的州包括佛蒙特州、俄克拉荷马州、怀俄明州、威斯康星州和爱荷华州，而阿拉巴马州、弗吉尼亚州、马萨诸塞州、康涅狄格州和佐治亚州的死亡率最低。结论：研究结果表明，与肥胖相关的IHD死亡率增加了2.5倍，突出了有针对性的公共卫生干预和进一步研究的必要性，以解决这一日益严重的公共卫生问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.80

自引率

5.90%

发文量

期刊介绍： Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.