Francois Rheault, Helen Mayberg, Michel Thiebaut de Schotten, Alard Roebroeck, Stephanie J Forkel
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引用次数: 0
Abstract
Tractography has emerged as a central tool for mapping the cerebral white matter architecture. However, its scientific value continues to be a subject of debate, given its inherent limitations in anatomical accuracy. This concise communication showcases key points of a debate held at the 2024 Tract-Anat Retreat, addressing the trade-offs between the accuracy and utility of tractography. While tractography remains constrained by limitations related to resolution, sensitivity, and validation, its usefulness and utility in areas such as surgical planning, disorder prediction, and the elucidation of brain development are emphasized. These perspectives highlight the necessity of context-specific interpretation, anatomically informed algorithms, and the continuous refinement of tractography workflows to achieve an optimal balance between accuracy and utility.
期刊介绍：
Brain Structure & Function publishes research that provides insight into brain structure−function relationships. Studies published here integrate data spanning from molecular, cellular, developmental, and systems architecture to the neuroanatomy of behavior and cognitive functions. Manuscripts with focus on the spinal cord or the peripheral nervous system are not accepted for publication. Manuscripts with focus on diseases, animal models of diseases, or disease-related mechanisms are only considered for publication, if the findings provide novel insight into the organization and mechanisms of normal brain structure and function.
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