Multi-regional sequential pain syndrome.

IF 2.7 3区医学 Q2 CLINICAL NEUROLOGY

Frontiers in Neurology Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI:10.3389/fneur.2025.1553455

Xiao Yang, Kai-Jun Zhao, Jian-Min Liu

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引用次数: 0

Abstract

Objective: To report a novel clinical entity, "Multi-regional Sequential Pain Syndrome" (MRSPS), and evaluate the relationship between hypoperfusion, cryptogenic vertebral artery dissection (CVAD), and MRSPS.

Methods: A 59-year-old female patient, with a chronic MRSPS condition spanning 10-30 years, underwent a comprehensive diagnostic evaluation including cranial CTA, MRI, DSA, and CT perfusion, culminating in the identification of CVAD via dynamic contrast-enhanced computed tomography (DCE-CT). The treatment strategy integrated repairing CVADs with stent implantation to address the hypoperfusion and MRSPS.

Results: Following intervention, hypoperfusion achieved complete improvement, and the patient achieved the complete resolution of pain and vertigo, with the modified Rankin Scale (mRS) score of 0 at the 1-year follow-up, signifying full neurological recovery.

Conclusion: CVADs, a key cause of brain tissue hypoperfusion in MRSPS, can be effectively treated by repair to alleviate the syndrome.

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多区域序列性疼痛综合征。

目的：报道一种新的临床实体“多区域序列性疼痛综合征”（MRSPS），并评估灌注不足、隐源性椎动脉夹层（CVAD）与MRSPS之间的关系。方法：一名59岁的女性患者，患有慢性MRSPS疾病，时间长达10-30 年，接受了全面的诊断评估，包括颅脑CTA， MRI， DSA和CT灌注，最终通过动态对比增强计算机断层扫描（DCE-CT）确定了CVAD。治疗策略采用支架置入术和修复术相结合的方法来解决低灌注和MRSPS问题。结果：干预后，低灌注完全改善，患者疼痛和眩晕完全缓解，1年随访时改良Rankin量表（mRS）评分为0分，神经功能完全恢复。结论：CVADs是MRSPS患者脑组织灌注不足的主要原因，可通过修复术有效治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Neurology CLINICAL NEUROLOGYNEUROSCIENCES -NEUROSCIENCES

CiteScore

4.90

自引率

8.80%

发文量

2792

审稿时长

14 weeks

期刊介绍： The section Stroke aims to quickly and accurately publish important experimental, translational and clinical studies, and reviews that contribute to the knowledge of stroke, its causes, manifestations, diagnosis, and management.