Chitosan-supported CuI-catalyzed cascade reaction of 2-halobenzoic acids and amidines for the synthesis of quinazolinones.

IF 2.2 4区化学 Q2 CHEMISTRY, ORGANIC

Beilstein Journal of Organic Chemistry Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI:10.3762/bjoc.21.67

Xuhong Zhao, Weishuang Li, Mengli Yang, Bojie Li, Yaoyao Zhang, Lizhen Huang, Lei Zhu

引用次数: 0

Abstract

A chitosan-supported CuI (CS@CuI) catalyst was developed for the synthesis of quinazolinones from 2-halobenzoic acids (including iodine and bromine) and amidines. The reaction proceeds under mild reaction conditions, demonstrating a broad substrate scope (30 examples) and good catalytic efficiency (up to 99% yield).

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壳聚糖负载cui催化2-卤代苯甲酸与脒级联反应合成喹唑啉酮。

以2-卤代苯甲酸（包括碘和溴）和脒为原料，制备了壳聚糖负载的CuI （CS@CuI）催化剂。该反应在温和的反应条件下进行，显示出广泛的底物范围（30个样品）和良好的催化效率（产率高达99%）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Beilstein Journal of Organic Chemistry 化学-有机化学

CiteScore

4.90

自引率

3.70%

发文量

167

审稿时长

1.4 months

期刊介绍： The Beilstein Journal of Organic Chemistry is an international, peer-reviewed, Open Access journal. It provides a unique platform for rapid publication without any charges (free for author and reader) – Platinum Open Access. The content is freely accessible 365 days a year to any user worldwide. Articles are available online immediately upon publication and are publicly archived in all major repositories. In addition, it provides a platform for publishing thematic issues (theme-based collections of articles) on topical issues in organic chemistry. The journal publishes high quality research and reviews in all areas of organic chemistry, including organic synthesis, organic reactions, natural product chemistry, structural investigations, supramolecular chemistry and chemical biology.