Mapping the evolution of mitochondrial dynamics research: A bibliometric analysis of global trends and collaborations.

IF 2.1 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Fugang Huang, Ke Sun, Zexuan Wu, Guanqun Xie, Jie Bao, Yongsheng Fan
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引用次数: 0

Abstract

Background: Mitochondrial dynamics is an important field in cell biology, encompassing mitochondrial fission and fusion. The balance between fission and fusion is responsible for the stability of the mitochondrial network and can be a regulator of mitochondrial function. Recent studies have emphasized that an imbalance in mitochondrial dynamics is the root cause of dysfunction and is involved in various stages, such as oxidative stress, inflammation and apoptosis. Reversing this imbalance can effectively alleviate disease conditions. Although the importance of mitochondrial dynamics has been widely recognized, there is still a lack of literature on the qualitative and quantitative description and analysis of advances in this field.

Objectives: This study is a bibliometric analysis of research trends, collaboration networks and thematic evolution in mitochondrial dynamics from 2000 to 2023.

Material and methods: Using the Web of Science Core Collection (WoSCC) database, we performed a bibliometric review, applying VOSviewer and CiteSpace to visualize and analyze publications, citations, collaborations, and key word trends.

Results: We analyzed 332 publications, identifying China and the USA as leaders in research output and international collaborations. Significant contributions were made by institutions like Chiang Mai University and the California Institute of Technology (Caltech), with major research shifts from basic mitochondrial functions to roles in diseases like Alzheimer's and cardiovascular disease.

Conclusion: Mitochondrial dynamics research has expanded, with increasing attention to its role in disease mechanisms. Future research should further explore these connections, potentially leading to innovative treatments.

绘制线粒体动力学研究的演变:全球趋势和合作的文献计量学分析。
背景:线粒体动力学是细胞生物学的一个重要领域,包括线粒体裂变和融合。裂变和融合之间的平衡负责线粒体网络的稳定性,并可以成为线粒体功能的调节器。最近的研究强调,线粒体动力学失衡是功能障碍的根本原因,涉及氧化应激、炎症和细胞凋亡等各个阶段。扭转这种不平衡可以有效地缓解疾病状况。虽然线粒体动力学的重要性已被广泛认识,但仍然缺乏对该领域进展的定性和定量描述和分析的文献。目的:本研究对2000年至2023年线粒体动力学的研究趋势、合作网络和专题演变进行了文献计量分析。材料和方法:利用Web of Science Core Collection (WoSCC)数据库,利用VOSviewer和CiteSpace对出版物、引文、合作和关键词趋势进行可视化分析,进行文献计量学综述。结果:我们分析了332份出版物,确定中国和美国在研究产出和国际合作方面处于领先地位。清迈大学(Chiang Mai University)和加州理工学院(Caltech)等机构做出了重大贡献,主要研究从基本的线粒体功能转向了阿尔茨海默氏症和心血管疾病等疾病的作用。结论:线粒体动力学研究不断扩大,其在疾病机制中的作用日益受到关注。未来的研究应该进一步探索这些联系,可能导致创新的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Advances in Clinical and Experimental Medicine
Advances in Clinical and Experimental Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
3.70
自引率
4.80%
发文量
153
审稿时长
6-12 weeks
期刊介绍: Advances in Clinical and Experimental Medicine has been published by the Wroclaw Medical University since 1992. Establishing the medical journal was the idea of Prof. Bogumił Halawa, Chair of the Department of Cardiology, and was fully supported by the Rector of Wroclaw Medical University, Prof. Zbigniew Knapik. Prof. Halawa was also the first editor-in-chief, between 1992-1997. The journal, then entitled "Postępy Medycyny Klinicznej i Doświadczalnej", appeared quarterly. Prof. Leszek Paradowski was editor-in-chief from 1997-1999. In 1998 he initiated alterations in the profile and cover design of the journal which were accepted by the Editorial Board. The title was changed to Advances in Clinical and Experimental Medicine. Articles in English were welcomed. A number of outstanding representatives of medical science from Poland and abroad were invited to participate in the newly established International Editorial Staff. Prof. Antonina Harłozińska-Szmyrka was editor-in-chief in years 2000-2005, in years 2006-2007 once again prof. Leszek Paradowski and prof. Maria Podolak-Dawidziak was editor-in-chief in years 2008-2016. Since 2017 the editor-in chief is prof. Maciej Bagłaj. Since July 2005, original papers have been published only in English. Case reports are no longer accepted. The manuscripts are reviewed by two independent reviewers and a statistical reviewer, and English texts are proofread by a native speaker. The journal has been indexed in several databases: Scopus, Ulrich’sTM International Periodicals Directory, Index Copernicus and since 2007 in Thomson Reuters databases: Science Citation Index Expanded i Journal Citation Reports/Science Edition. In 2010 the journal obtained Impact Factor which is now 1.179 pts. Articles published in the journal are worth 15 points among Polish journals according to the Polish Committee for Scientific Research and 169.43 points according to the Index Copernicus. Since November 7, 2012, Advances in Clinical and Experimental Medicine has been indexed and included in National Library of Medicine’s MEDLINE database. English abstracts printed in the journal are included and searchable using PubMed http://www.ncbi.nlm.nih.gov/pubmed.
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