Association between Dietary Patterns and Incident Hypertension in Regards (Reasons for Geographic and Regional Differences in Stroke) Participants.

IF 3.1 3区医学 Q2 PERIPHERAL VASCULAR DISEASE

American Journal of Hypertension Pub Date : 2025-07-15 DOI:10.1093/ajh/hpaf063

Kara F Morton, John Emerson Scheinuk, John Emerson Scheinuk, Sarah Bowman, Hely D Nanavati, Stephen A Clarkson, Vera Bittner, Kim A Williams, Timothy B Plante, James M Shikany, Suzanne E Judd

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引用次数: 0

Abstract

Background: Diet contributes to the development of hypertension. We examined associations between five dietary patterns and incident hypertension in the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.

Methods: Participants without prevalent hypertension (blood pressure < 130/80 mmHg or antihypertensive medication use) were evaluated at baseline and follow-up. Dietary patterns were developed using food frequency questionnaires. Diet adherence was divided into quartiles, and Modified Poisson regression estimated risk ratios of incident hypertension by quartile. We adjusted for covariates sequentially. Sex and race interactions were tested with a priori stratified analyses. An identical sensitivity analysis was completed using the Joint National Comission-7 definition of hypertension, the prevailing hypertension definition at the time of enrollment (>140/90 mmHg or antihypertensive medication use).

Results: Of 30,239 REGARDS participants, 3,423 met inclusion criteria and 1,439 (42.0%) developed hypertension. Participants highly adherent to the Alcohol/Salad pattern had an increased risk of incident hypertension [RR = 1.12, 95% CI (1.00, 1.27)]. This persisted in White females after controlling for alcohol [RR = 1.27, 95% CI (1.04, 1.54)]. The remaining dietary patterns had no associations in fully adjusted models. Sex/race interactions were not significant. The sensitivity analysis included 6,582 participants, of whom 2,295 (34.9%) developed hypertension. No associations were found between diet and incident hypertension in fully adjusted models.

Conclusions: The Alcohol/Salad dietary pattern portends the highest risk of incident hypertension. No further associations existed between other dietary patterns and incident hypertension after adjusting for covariates. Our findings suggest that diet is contributory, but not an exclusive cause, of incident hypertension.

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在REGARDS（卒中的地理和区域差异的原因）参与者中，饮食模式与高血压发病率之间的关系。

背景：饮食有助于高血压的发展。我们在脑卒中地理和种族差异的原因（REGARDS）队列中研究了五种饮食模式与高血压发病率之间的关系。方法：无高血压（血压140/90 mmHg或使用降压药）的受试者。结果：30239名REGARDS参与者中，3423人符合纳入标准，1439人（42.0%）患高血压。高度坚持酒精/沙拉模式的参与者发生高血压的风险增加[RR=1.12, 95% CI(1.00, 1.27)]。在控制酒精后，这种情况在白人女性中仍然存在[RR=1.27, 95% CI(1.04, 1.54)]。其余的饮食模式在完全调整后的模型中没有关联。性别/种族的相互作用不显著。敏感性分析包括6582名参与者，其中2295人（34.9%）患高血压。在完全调整的模型中，没有发现饮食和高血压之间的关联。结论：酒精/沙拉饮食模式预示着高血压发生的最高风险。在调整协变量后，其他饮食模式与高血压发病率之间没有进一步的关联。我们的研究结果表明，饮食是导致高血压的原因之一，但不是唯一的原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Hypertension 医学-外周血管病

CiteScore

6.90

自引率

6.20%

发文量

144

审稿时长

3-8 weeks

期刊介绍： The American Journal of Hypertension is a monthly, peer-reviewed journal that provides a forum for scientific inquiry of the highest standards in the field of hypertension and related cardiovascular disease. The journal publishes high-quality original research and review articles on basic sciences, molecular biology, clinical and experimental hypertension, cardiology, epidemiology, pediatric hypertension, endocrinology, neurophysiology, and nephrology.