Association of obesity traits and uric acid levels with cardiovascular disease in Punjabi patients from Faisalabad, Pakistan.

IF 2.1 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Acta cardiologica Pub Date : 2025-04-14 DOI:10.1080/00015385.2025.2490369

Muhammad Umer Ghori, Muhammad Shareef Masoud, Muhammad Shafique, Misbah Hussain, Fazli Rabbi Awan

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引用次数: 0

Abstract

Background: Cardiovascular diseases (CVDs) are one of the significant public health concerns worldwide. Understanding the relationship between Body Mass Index (BMI), Waist Circumference (WC), Waist-to-Hip Ratio (WHR) and uric acid levels are important in assessing cardiovascular risk. This study aimed to investigate the associations of BMI, WHR, WC and several biochemical parameters including uric acid levels with cardiovascular disease in patients from Faisalabad, Pakistan.

Methods: This is a Retrospective Observational Study. A total of 403 cardiovascular patients were enrolled. Anthropometric measurements including BMI, WC and WHR were recorded. Serum samples were used to measure various biochemical parameters. SPSS ver. 21 was used to perform statistical analyses.

Results: Results showed that BMI (29%↑), waist circumference (7%↑) and hip circumference (8%↑) were higher in obese CVD patients as compared to non-obese CVD patients. Additionally, uric acid levels were high (11%↑) in male CVD patients as compared to female CVD patients while total cholesterol (8%↑) and triglycerides (20%↑) levels were higher in female CVD patients as compared to male CVD patients. Pearson correlation and Linear regression analysis confirmed that uric acid was associated with total cholesterol, triglycerides, alanine transaminase, creatinine and urea levels (p < 0.05).

Conclusion: This study confirms the associations between BMI, WC, WHR, uric acid levels and multiple biochemical parameters with health status in cardiovascular patients from Faisalabad, Pakistan.

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巴基斯坦费萨拉巴德旁遮普邦患者肥胖特征和尿酸水平与心血管疾病的关系

背景：心血管疾病（cvd）是世界范围内重要的公共卫生问题之一。了解身体质量指数（BMI）、腰围（WC）、腰臀比（WHR）和尿酸水平之间的关系对评估心血管风险很重要。本研究旨在调查巴基斯坦费萨拉巴德（Faisalabad）患者的BMI、WHR、WC和一些生化参数（包括尿酸水平）与心血管疾病的关系。方法：回顾性观察性研究。共有403名心血管患者入组。记录人体测量数据，包括BMI、WC和WHR。采用血清样品测定各项生化指标。SPSS版本。21进行统计分析。结果：结果显示肥胖CVD患者的BMI（29%↑）、腰围（7%↑）和臀围（8%↑）均高于非肥胖CVD患者。此外，与女性CVD患者相比，男性CVD患者的尿酸水平较高（11%↑），而女性CVD患者的总胆固醇（8%↑）和甘油三酯（20%↑）水平高于男性CVD患者。Pearson相关和线性回归分析证实了尿酸与总胆固醇、甘油三酯、丙氨酸转氨酶、肌酐和尿素水平相关(p)。结论：本研究证实了BMI、WC、WHR、尿酸水平和多个生化参数与巴基斯坦Faisalabad心血管患者健康状况的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta cardiologica 医学-心血管系统

CiteScore

2.50

自引率

12.50%

发文量

115

审稿时长

2 months

期刊介绍： Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.