Effectiveness of myofascial therapy (MFT) along with traditional physiotherapy and intermittent prophylaxis on short-term improvement of joint health in hemophilic arthropathy: a randomized control trial.

IF 2.3 4区医学 Q2 HEMATOLOGY

Expert Review of Hematology Pub Date : 2025-06-01 Epub Date: 2025-04-25 DOI:10.1080/17474086.2025.2495674

Mridul Makkar, Mullai S Dhinakaran, Prateek Shukla, Diksha Sarwan, Soumya Ojha, M Joseph John

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引用次数: 0

Abstract

Background: Myofascial therapy (MFT) works on biomechanical soft tissue loading principles aimed to reduce pain, improve tissue mobility and function.

Aim: To find effectiveness of MFT and traditional physiotherapy with intermittent prophylaxis on short-term improvement of joint health in hemophilic arthropathy.

Research design and methods: Thirty-one patients with Hemophilia A and joint arthropathy (elbows and/or knees) were randomly divided into MFT group (MFT + traditional physiotherapy) and control group (traditional physiotherapy). Both groups received four physiotherapy sessions per week for three weeks and FVIII prophylaxis twice weekly. Haemophilia Joint Health Score (HJHS), Functional Independence Scoring for Haemophilia (FISH), and Range of Motion (ROM) were assessed on Day 0, 10, 21.

Results: MFT group demonstrated a significant improvement in their overall HJHS scores (p = 0.016, d = 0.93) and HJHS knee joint scores (p = 0.007, d = 0.57) compared to control group participants. ROM increased substantially in MFT group relative to control group (18.97%; 10.10% improvement in knee and elbow ROM, respectively, vs 9.49%; 1.25%). There was an improvement in FISH scores in both groups, with a slightly greater improvement in control group (13.68% vs 11.08%).

Conclusions: MFT is effective and feasible in short-term improvement of joint health in Hemophilia A patients with elbow and knee arthropathy.

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肌筋膜疗法（MFT）联合传统物理疗法和间歇性预防对血友病关节健康短期改善的有效性：一项随机对照试验

背景：肌筋膜疗法（MFT）是一种基于生物力学的软组织负荷疗法，旨在减轻疼痛，改善组织活动和功能。目的：探讨MFT与传统物理治疗联合间歇预防对血友病关节健康的短期改善效果。研究设计与方法：将31例A型血友病合并关节病变（肘部和/或膝关节）患者随机分为MFT组（MFT +传统物理治疗）和对照组（传统物理治疗）。两组患者每周接受四次物理治疗，持续三周，每周接受两次FVIII预防治疗。在第0、10、21天分别评估血友病关节健康评分（HJHS）、血友病功能独立评分（FISH）和活动范围（ROM）。结果：与对照组相比，MFT组患者HJHS总分（p = 0.016, d = 0.93）和HJHS膝关节评分（p = 0.007, d = 0.57）均有显著提高。MFT组相对于对照组ROM显著升高(18.97%；膝关节和肘部ROM分别改善10.10%和9.49%；1.25%)。两组患者FISH评分均有改善，对照组改善幅度略大（13.68% vs 11.08%）。结论：MFT短期改善A型血友病伴肘关节病变患者关节健康是有效可行的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Hematology HEMATOLOGY-

CiteScore

4.70

自引率

3.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Advanced molecular research techniques have transformed hematology in recent years. With improved understanding of hematologic diseases, we now have the opportunity to research and evaluate new biological therapies, new drugs and drug combinations, new treatment schedules and novel approaches including stem cell transplantation. We can also expect proteomics, molecular genetics and biomarker research to facilitate new diagnostic approaches and the identification of appropriate therapies. Further advances in our knowledge regarding the formation and function of blood cells and blood-forming tissues should ensue, and it will be a major challenge for hematologists to adopt these new paradigms and develop integrated strategies to define the best possible patient care. Expert Review of Hematology (1747-4086) puts these advances in context and explores how they will translate directly into clinical practice.