Association Between Carotid Plaque Characteristics and High-risk Coronary Plaque: A Virtual Histology Intravascular Ultrasound Study.

IF 2.2 3区 医学 Q2 PERIPHERAL VASCULAR DISEASE
Peng Yan, Xinhao Yang, Zhengyu Yang, Hailing Wang, Jiehong Yuan, Maoyu Li, Xiaotong Ma, Xiang Wang, Qinjian Sun
{"title":"Association Between Carotid Plaque Characteristics and High-risk Coronary Plaque: A Virtual Histology Intravascular Ultrasound Study.","authors":"Peng Yan, Xinhao Yang, Zhengyu Yang, Hailing Wang, Jiehong Yuan, Maoyu Li, Xiaotong Ma, Xiang Wang, Qinjian Sun","doi":"10.1177/00033197251333204","DOIUrl":null,"url":null,"abstract":"<p><p>This retrospective study aimed to investigate the association between carotid artery plaque characteristics evaluated by virtual histology intravascular ultrasound (VH-IVUS) and high-risk coronary plaques determined by coronary computed tomography angiography (CCTA) among patients (<i>n</i> = 72) who underwent carotid artery stenting (CAS). VH-IVUS examination was performed during CAS and CCTA examination before CAS. Logistic regression models were used to explore the association between carotid plaque characteristics and high-risk coronary plaque. Of 72 patients, 46 (63.9%) were diagnosed as having high-risk coronary plaques. The necrotic core (NC) area, NC percentage, dense calcium (DC) area, and symptomatic carotid artery stenosis were significantly associated with high-risk coronary plaques (all <i>P</i> <i><</i> .05). Isolated upper-NC area, and upper-NC area combined with upper-DC area were associated with high-risk coronary plaques. Compared with the lower-NC area and lower-DC area groups, participants with upper-NC area and upper-NC area had 12.53 times higher odds ratio of having high-risk coronary plaques. This study showed that the NC area, NC percentage, DC area and symptomatic carotid artery stenosis were associated with high-risk coronary plaques. Participants with both upper-NC area and upper-DC area might have a higher risk of high-risk coronary plaques.</p>","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"33197251333204"},"PeriodicalIF":2.2000,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00033197251333204","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0

Abstract

This retrospective study aimed to investigate the association between carotid artery plaque characteristics evaluated by virtual histology intravascular ultrasound (VH-IVUS) and high-risk coronary plaques determined by coronary computed tomography angiography (CCTA) among patients (n = 72) who underwent carotid artery stenting (CAS). VH-IVUS examination was performed during CAS and CCTA examination before CAS. Logistic regression models were used to explore the association between carotid plaque characteristics and high-risk coronary plaque. Of 72 patients, 46 (63.9%) were diagnosed as having high-risk coronary plaques. The necrotic core (NC) area, NC percentage, dense calcium (DC) area, and symptomatic carotid artery stenosis were significantly associated with high-risk coronary plaques (all P< .05). Isolated upper-NC area, and upper-NC area combined with upper-DC area were associated with high-risk coronary plaques. Compared with the lower-NC area and lower-DC area groups, participants with upper-NC area and upper-NC area had 12.53 times higher odds ratio of having high-risk coronary plaques. This study showed that the NC area, NC percentage, DC area and symptomatic carotid artery stenosis were associated with high-risk coronary plaques. Participants with both upper-NC area and upper-DC area might have a higher risk of high-risk coronary plaques.

颈动脉斑块特征与高危冠状动脉斑块之间的关系:一项虚拟组织学血管内超声研究。
本回顾性研究旨在探讨在接受颈动脉支架植入术(CAS)的患者(n = 72)中,通过虚拟组织学血管内超声(VH-IVUS)评估的颈动脉斑块特征与冠状动脉计算机断层血管造影(CCTA)确定的高危冠状动脉斑块之间的关系。在CAS时行VH-IVUS检查,CAS前行CCTA检查。采用Logistic回归模型探讨颈动脉斑块特征与高危冠状动脉斑块之间的关系。72例患者中,46例(63.9%)被诊断为高危冠状动脉斑块。坏死核(NC)面积、NC百分比、致密钙(DC)面积、症状性颈动脉狭窄与高危斑块有显著相关性(P < 0.05)。孤立的上nc区、上nc区合并上dc区与高危冠状动脉斑块相关。与低nc区组和低dc区组相比,高nc区组和高nc区组的高危冠状动脉斑块的优势比高出12.53倍。本研究显示,NC面积、NC百分比、DC面积及症状性颈动脉狭窄与高危冠状动脉斑块相关。上nc区和上dc区均存在的受试者发生高危冠状动脉斑块的风险较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Angiology
Angiology 医学-外周血管病
CiteScore
5.50
自引率
14.30%
发文量
180
审稿时长
6-12 weeks
期刊介绍: A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信