ChatGPT-4 vs. multi-disciplinary tumor board decisions for the therapeutic management of primary laryngeal cancer.

IF 1.2 4区医学 Q3 OTORHINOLARYNGOLOGY

Acta Oto-Laryngologica Pub Date : 2025-05-13 DOI:10.1080/00016489.2025.2502563

Erim Pamuk, Yaşar Enez Bilen, Çağrı Külekçi, Oğuz Kuşcu

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引用次数: 0

Abstract

Background: Artificial intelligence-based clinical decision support systems are promising tools for addressing the increasing complexity of oncological data and treatment. However, the integration and validation of models such as ChatGPT within multidisciplinary decision-making processes for head and neck cancers remain limited.

Objective: To evaluate the performance of ChatGPT-4 in the management of primary laryngeal cancer and compare it with multidisciplinary tumor board (MDT) decisions.

Methods: The medical records of 25 patients with untreated laryngeal cancer were evaluated using ChatGPT-4 for therapeutic recommendations. The coherence of responses was graded from Grade 1 (totally coherent) to Grade 4 (totally incoherent) and compared with actual MDT decisions. The association between patient features and response grades was also assessed.

Results: ChatGPT-4 provided totally coherent (Grade 1) responses consistent with MDT decisions in 72% of the patients. The rates of Grade 2 and Grade 3 coherent responses were 20% and 8%, respectively. There were no totally incoherent responses. There was no significant association between the grade of coherence and T stage, N stage, tumor localization, differentiation, or age (p = 0.106, p = 0.588, p = 0.271, p = 0.677, p = 0.506, respectively).

Conclusion: With further improvements, ChatGPT-4 can be a promising adjunct tool for clinicians in decision-making for primary laryngeal cancer.

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ChatGPT-4与多学科肿瘤委员会决定原发性喉癌的治疗管理。

背景：基于人工智能的临床决策支持系统是解决日益复杂的肿瘤数据和治疗的有前途的工具。然而，在头颈部癌症的多学科决策过程中，ChatGPT等模型的整合和验证仍然有限。目的：评价ChatGPT-4在原发性喉癌治疗中的作用，并将其与多学科肿瘤委员会（MDT）决策进行比较。方法：采用ChatGPT-4对25例未经治疗的喉癌患者的病历进行评价，提出治疗建议。反应的连贯性从1级（完全连贯）到4级（完全不连贯）进行分级，并与实际MDT决策进行比较。还评估了患者特征与反应等级之间的关系。结果：ChatGPT-4在72%的患者中提供了完全一致的（1级）反应，与MDT决定一致。2级和3级连贯反应率分别为20%和8%。没有完全不连贯的回答。一致性分级与T分期、N分期、肿瘤定位、分化、年龄无显著相关性（p = 0.106、p = 0.588、p = 0.271、p = 0.677、p = 0.506）。结论：随着进一步的改进，ChatGPT-4有望成为临床医生决定原发性喉癌的辅助工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Oto-Laryngologica 医学-耳鼻喉科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.