Detection of precancerous lesions in cervical images of perimenopausal women using U-net deep learning.

Abstract

Due to physiological changes during the perimenopausal period, the morphology of cervical cells undergoes certain alterations. Accurate cell image segmentation and lesion identification are of great significance for the early detection of precancerous lesions. Traditional detection methods may have certain limitations, thereby creating an urgent need for the development of more effective models. This study aimed to develop a highly efficient and accurate cervical cell image segmentation and recognition model to enhance the detection of precancerous lesions in perimenopausal women. based on U-shaped Network(U-Net) and Residual Network (ResNet). The model integrates U-Net with Segmentation Network (SegNet) and incorporates the Squeeze-and-Excitation (SE) attention mechanism to create the 2Se/U-Net segmentation model. Additionally, ResNet is optimized with the local discriminant loss function (LD-loss) and deep residual learning (DRL) blocks to develop the LD/ResNet lesion recognition model. The performance of the models is evaluated using data from 103 cytology images of perimenopausal women, focusing on segmentation metrics like mean pixel accuracy (MPA) and mean intersection over union (mIoU), as well as lesion detection metrics such as accuracy (Acc), precision (Pre), recall (Re), and F1-score (F1). Results show that the 2Se/U-Net model achieves an MPA of 92.63% and mIoU of 96.93%, outperforming U-Net by 12.48% and 9.47%, respectively. The LD/ResNet model demonstrates over 97.09% accuracy in recognizing cervical cells and achieves high detection performance for precancerous lesions, with Acc, Pre, and Re at 98.95%, 99.36%, and 98.89%, respectively. The model shows great potential for enhancing cervical cancer screening in clinical settings.