Inducing emesis in Australian dogs and cats: agents, adverse effects and antiemetic administration.

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES
J Tsitonakis, E Hall, A Quain
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引用次数: 0

Abstract

Objective: To describe the agents used by Australian veterinarians in inducing emesis in dogs and cats, adverse effects and antiemetic administration.

Methods: An anonymous online mixed-methods survey incorporating closed and open-ended questions was distributed to Australian veterinarians via e-newsletters and social media between April and June 2024.

Results: From 317 valid responses, 316 respondents induced emesis in a dog (99.7%) and 128 (40.4%) induced emesis in a cat in the previous 12 months. The most common protocols were subcutaneous injection of apomorphine (n = 310/316, 98.1%) for dogs and intramuscular injection of dexmedetomidine or medetomidine (n = 79/128, 61.7%) for cats. Respondents reported significantly reduced success (n = 74/128, 57.8%) inducing emesis in cats compared with dogs (n = 312/316, 98.7%) (P ≤ 0.001). Sedation was the most reported adverse effect for both species. The subconjunctival route of apomorphine was found to significantly increase the risk of adverse effects in dogs, compared with the subcutaneous route (P = 0.03). Antiemetics were more frequently administered to dogs than cats. Univariable logistical regression analysis revealed that veterinarians with fewer than 5 years' experience were significantly more likely to use an antiemetic drug when inducing vomiting in dogs (P = 0.05) compared with veterinarians with 31 or more years of experience.

Conclusion: These findings enable clinicians to benchmark practices against those of their peers, characterise adverse effects associated with emesis induction and refine their technique to improve patient welfare. A more reliable means of inducing emesis in cats is needed.

诱发呕吐在澳大利亚狗和猫:代理人,不良反应和止吐管理。
目的:介绍澳大利亚兽医用于犬猫催吐的药物、不良反应和止吐给药情况。方法:在2024年4月至6月期间,通过电子通讯和社交媒体向澳大利亚兽医分发了一项包含封闭式和开放式问题的匿名在线混合方法调查。结果:在过去的12个月中,317份有效回复中,316份(99.7%)致狗呕吐,128份(40.4%)致猫呕吐。最常见的治疗方案是犬皮下注射阿波啡(n = 310/316, 98.1%),猫肌肉注射右美托咪定或美托咪定(n = 79/128, 61.7%)。受访者报告猫诱导呕吐的成功率(n = 74/128, 57.8%)明显低于狗(n = 312/316, 98.7%) (P≤0.001)。镇静是两个物种中最常见的不良反应。与皮下给药相比,结膜下给药可显著增加犬的不良反应风险(P = 0.03)。止吐药更常用于狗而不是猫。单变量logistic回归分析显示,经验少于5年的兽医在诱导狗呕吐时使用止吐药物的可能性明显高于经验≥31年的兽医(P = 0.05)。结论:这些发现使临床医生能够对他们的同行进行基准实践,描述与呕吐诱导相关的不良反应,并改进他们的技术以改善患者的福利。需要一种更可靠的方法来诱导猫呕吐。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Australian Veterinary Journal
Australian Veterinary Journal 农林科学-兽医学
CiteScore
2.40
自引率
0.00%
发文量
85
审稿时长
18-36 weeks
期刊介绍: Over the past 80 years, the Australian Veterinary Journal (AVJ) has been providing the veterinary profession with leading edge clinical and scientific research, case reports, reviews. news and timely coverage of industry issues. AJV is Australia''s premier veterinary science text and is distributed monthly to over 5,500 Australian Veterinary Association members and subscribers.
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