The Impact of Red Blood Cell Count and Hemoglobin Levels on Bone Remodeling in Mandibular Angle Osteotomy.

IF 2 3区医学 Q2 SURGERY

Aesthetic Plastic Surgery Pub Date : 2025-05-12 DOI:10.1007/s00266-025-04854-4

Zhiyang Xie, Shunchao Yan, Chongxu Qiao, Zai Shi, Jingyi Xu, Kaili Yan, Yuming Qu, Shu Wang, Wensong Shangguan, Guoping Wu

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引用次数: 0

Abstract

Background: Previous studies have identified bone remodeling in the mandibular angle region (MAR) as a key factor influencing outcomes after mandibular angle osteotomy (MAO). This study investigates hematologic predictors-red blood cell (RBC) count and hemoglobin (Hb) levels-and their correlation with postoperative MAR bone remodeling.

Methods: A retrospective analysis was conducted on 135 patients who underwent MAO between January 2015 and December 2022. Bone remodeling was assessed using cone beam computed tomography (CBCT) imaging at two time points: T1 (immediately postoperatively) and T2 (at least 12months postoperatively). Quantification of bone remodeling was performed using Geomagic Wrap 2021. Patients were categorized into bone stability (S), bone regeneration (RG), and bone resorption (RS) groups based on MAR deviations (thresholds: > + 0.1 mm regeneration, < - 0.1 mm resorption, within ± 0.1 mm stability). Statistical analyses, including Kruskal-Wallis tests with post hoc analysis and logistic regression models, were performed to assess associations between RBC count, Hb levels, and bone remodeling outcomes.

Results: Patients with higher preoperative RBC and Hb levels exhibited significantly greater bone remodeling than those with lower levels (p < 0.05). Remodeling was particularly evident in the mandibular angle region. Multivariate analysis confirmed RBC and Hb levels as independent predictors of favorable bone remodeling. A 1 × 10¹² increase in RBC count was associated with a 2.558-fold higher likelihood of postoperative bone regeneration (OR: 2.558, 95% CI: 1.098-5.958, P = 0.030), while a 1 g/L increase in Hb levels increased the probability of bone regeneration by 1.036 times (OR:1.036, 95% CI: 1.006-1.066, P = 0.017).

Conclusions: This study highlights RBC count and Hb levels as potential biomarkers influencing bone remodeling after MAO. These findings suggest that hematologic parameters should be considered during preoperative planning to optimize surgical outcomes and reduce the need for revision procedures.

Level of evidence iv: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

查看原文本刊更多论文

红细胞计数和血红蛋白水平对下颌角截骨术后骨重塑的影响。

背景：已有研究发现下颌角区骨重塑是影响下颌角截骨术（MAO）预后的关键因素。本研究探讨血液学预测指标——红细胞（RBC）计数和血红蛋白（Hb）水平——及其与术后MAR骨重塑的相关性。方法：对2015年1月至2022年12月期间接受MAO治疗的135例患者进行回顾性分析。在两个时间点：T1（术后立即）和T2（术后至少12个月）使用锥形束计算机断层扫描（CBCT）成像评估骨重塑。使用Geomagic Wrap 2021对骨重塑进行量化。根据MAR偏差（阈值：> + 0.1 mm再生）将患者分为骨稳定(S)、骨再生（RG）和骨吸收（RS）组。结果：术前RBC和Hb水平较高的患者比低水平的患者表现出更大的骨重塑（p12 RBC计数增加与术后骨再生可能性高2.558倍相关）(OR: 2.558, 95% CI：1.098-5.958, P = 0.030)，而Hb水平每增加1 g/L，骨再生的可能性增加1.036倍（OR:1.036, 95% CI: 1.006-1.066, P = 0.017）。结论：本研究强调红细胞计数和血红蛋白水平是影响MAO后骨重塑的潜在生物标志物。这些发现表明，术前计划时应考虑血液学参数，以优化手术效果，减少翻修手术的需要。证据等级iv：本刊要求作者为每篇文章指定一个证据等级。有关这些循证医学评级的完整描述，请参阅目录或在线作者说明www.springer.com/00266。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aesthetic Plastic Surgery 医学-外科

CiteScore

4.40

自引率

25.00%

发文量

479

审稿时长

3 months

期刊介绍： Aesthetic Plastic Surgery is a publication of the International Society of Aesthetic Plastic Surgery and the official journal of the European Association of Societies of Aesthetic Plastic Surgery (EASAPS), Società Italiana di Chirurgia Plastica Ricostruttiva ed Estetica (SICPRE), Vereinigung der Deutschen Aesthetisch Plastischen Chirurgen (VDAPC), the Romanian Aesthetic Surgery Society (RASS), Asociación Española de Cirugía Estética Plástica (AECEP), La Sociedad Argentina de Cirugía Plástica, Estética y Reparadora (SACPER), the Rhinoplasty Society of Europe (RSE), the Iranian Society of Plastic and Aesthetic Surgeons (ISPAS), the Singapore Association of Plastic Surgeons (SAPS), the Australasian Society of Aesthetic Plastic Surgeons (ASAPS), the Egyptian Society of Plastic and Reconstructive Surgeons (ESPRS), and the Sociedad Chilena de Cirugía Plástica, Reconstructiva y Estética (SCCP). Aesthetic Plastic Surgery provides a forum for original articles advancing the art of aesthetic plastic surgery. Many describe surgical craftsmanship; others deal with complications in surgical procedures and methods by which to treat or avoid them. Coverage includes "second thoughts" on established techniques, which might be abandoned, modified, or improved. Also included are case histories; improvements in surgical instruments, pharmaceuticals, and operating room equipment; and discussions of problems such as the role of psychosocial factors in the doctor-patient and the patient-public interrelationships. Aesthetic Plastic Surgery is covered in Current Contents/Clinical Medicine, SciSearch, Research Alert, Index Medicus-Medline, and Excerpta Medica/Embase.