Patient-reported Impact of Menopause and Hormone Replacement Therapy on Psoriasis.

IF 3.5 4区医学 Q1 DERMATOLOGY

Acta dermato-venereologica Pub Date : 2025-04-09 DOI:10.2340/actadv.v105.42843

Bo Young Chung, Chandler Johnson, Jin Seo Park, Kathryn Haran, Payton Smith, Allison Kranyak, Tina Bhutani, Wilson Liao

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引用次数: 0

Abstract

Menopause's impact on psoriasis remains unclear. This study's aim was to gather information on patient perception of the impact of menopause and hormone replacement therapy (HRT) on psoriasis. This survey-based study analysed 139 postmenopausal women with psoriasis from the USA and South Korea. In the combined cohort, most women reported menopause either had no effect on their psoriasis (41.7%) or worsened their psoriasis (33.1%). In the combined cohort, a majority of women (73.4%) reported that there was no change in their psoriasis treatment with menopause. Of the women receiving HRT (n = 29), the majority reported no effect on psoriasis (62.1%). In multivariate analysis, alcohol consumption was protective against worsening of psoriasis with menopause (OR 0.19 [95% CI 0.06-0.59], p = 0.004). In summary, this study showed that menopause is likely to have a neutral to negative effect on psoriasis. HRT was found to have no effect on the course of psoriasis in the majority of cases.

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患者报告的更年期和激素替代治疗对牛皮癣的影响。

更年期对牛皮癣的影响尚不清楚。本研究的目的是收集患者对更年期和激素替代疗法（HRT）对牛皮癣影响的认知信息。这项基于调查的研究分析了139名来自美国和韩国的绝经后牛皮癣妇女。在合并队列中，大多数女性报告更年期对牛皮癣没有影响（41.7%）或恶化牛皮癣（33.1%）。在合并队列中，大多数女性（73.4%）报告绝经后牛皮癣治疗没有变化。在接受HRT的妇女中（n = 29），大多数报告对牛皮癣没有影响（62.1%）。在多变量分析中，饮酒对绝经期牛皮癣恶化有保护作用（OR 0.19 [95% CI 0.06-0.59], p = 0.004）。总之，这项研究表明，更年期可能对牛皮癣有中性或负面的影响。在大多数情况下，激素替代疗法对牛皮癣的病程没有影响。

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来源期刊

Acta dermato-venereologica 医学-皮肤病学

CiteScore

4.90

自引率

2.80%

发文量

210

审稿时长

6-12 weeks

期刊介绍： Acta Dermato-Venereologica publishes high-quality manuscripts in English in the field of Dermatology and Venereology, dealing with new observations on basic dermatological and venereological research, as well as clinical investigations. Each volume also features a number of Review articles in special areas, as well as short Letters to the Editor to stimulate debate and to disseminate important clinical observations. Acta Dermato-Venereologica has rapid publication times and is amply illustrated with a large number of colour photographs.