{"title":"Intense FDG Activity of Renal Granuloma Following Intravesical Bacillus Calmette-Guérin Therapy for Bladder Cancer Mimicking Malignancy.","authors":"Xiaojun Man, Changming Dong, Xiandong Song, Aisheng Dong","doi":"10.1097/RLU.0000000000005810","DOIUrl":null,"url":null,"abstract":"<p><p>Intravesical bacillus Calmette-Guérin (BCG) therapy is an effective immunotherapy for superficial bladder cancer. BCG-related infectious complications may occur following intravesical BCG instillation. We describe contrast-enhanced CT, FDG PET/CT, and delayed abdominal FDG PET/MRI findings in a case of BCG-related renal granulomas following intravesical BCG therapy for bladder cancer. The renal lesions showed ill-defined margins with progressive enhancement on postcontrast CT, hypointensity on T2-weighted images, and variable FDG activity on both PET/CT and delayed PET/MRI. This case indicates that BCG-related renal granuloma should be included in the differential diagnosis of FDG-avid renal lesions in patients with BCG therapy for bladder cancer.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"960-962"},"PeriodicalIF":9.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000005810","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/23 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Intravesical bacillus Calmette-Guérin (BCG) therapy is an effective immunotherapy for superficial bladder cancer. BCG-related infectious complications may occur following intravesical BCG instillation. We describe contrast-enhanced CT, FDG PET/CT, and delayed abdominal FDG PET/MRI findings in a case of BCG-related renal granulomas following intravesical BCG therapy for bladder cancer. The renal lesions showed ill-defined margins with progressive enhancement on postcontrast CT, hypointensity on T2-weighted images, and variable FDG activity on both PET/CT and delayed PET/MRI. This case indicates that BCG-related renal granuloma should be included in the differential diagnosis of FDG-avid renal lesions in patients with BCG therapy for bladder cancer.
期刊介绍：
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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