The Prevalence and Characteristics of Anemia Among Newly-Diagnosed Patients with Leukemia in Saudi Arabia.

IF 0.7 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Clinical laboratory Pub Date : 2025-04-01 DOI:10.7754/Clin.Lab.2024.241002

Rana G Zaini, Wafa A Nawwab, Shmooa Alharthi, Nawal F Alboqami, Samiyah A Hazzazi, Thamer A Althubaity, Maryam A Altowirgi

{"title":"The Prevalence and Characteristics of Anemia Among Newly-Diagnosed Patients with Leukemia in Saudi Arabia.","authors":"Rana G Zaini, Wafa A Nawwab, Shmooa Alharthi, Nawal F Alboqami, Samiyah A Hazzazi, Thamer A Althubaity, Maryam A Altowirgi","doi":"10.7754/Clin.Lab.2024.241002","DOIUrl":null,"url":null,"abstract":"Background: Anemia in patients with leukemia results in poor quality of life (QOL) and increased risk of complications from chemotherapy. We aimed to identify the prevalence and characteristics of anemia among newly-diagnosed patients with acute and chronic leukemia.Methods: A retrospective cohort included all patients diagnosed with leukemia at King Faisal Medical Complex in Taif City, Saudia Aribia, from 2019 through 2023.Results: From 49 patients newly diagnosed with leukemia, 57% were males, and 40.8% were more than 60 years old. The prevalence of anemia was 83.6%. The mean hemoglobin level was 9.7 ± 3 g/dL. Furthermore, 36.7% had acute myeloid leukemia (AML), 36.7% had chronic lymphocytic leukemia (CLL), 22.5% had acute lymphoblastic leukemia (ALL), while only 2% had chronic myeloid leukemia (CML) and 2% had non-Hodgkin lymphoma (NHL). The most common type of anemia was normocytic normochromic anemia (55.6%), followed by macrocytic hyperchromic anemia (24.4%). All patients diagnosed with AML, ALL, CML, or NHL had anemia at time of diagnosis. However, the prevalence of anemia among patients diagnosed with CLL was 55%.Conclusions: Anemia is highly prevalent among patients with leukemia at time of diagnosis. Early identification and correction are crucial to improve QOL and reduce complications from chemotherapy.","PeriodicalId":10384,"journal":{"name":"Clinical laboratory","volume":"71 4","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical laboratory","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7754/Clin.Lab.2024.241002","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Anemia in patients with leukemia results in poor quality of life (QOL) and increased risk of complications from chemotherapy. We aimed to identify the prevalence and characteristics of anemia among newly-diagnosed patients with acute and chronic leukemia.

Methods: A retrospective cohort included all patients diagnosed with leukemia at King Faisal Medical Complex in Taif City, Saudia Aribia, from 2019 through 2023.

Results: From 49 patients newly diagnosed with leukemia, 57% were males, and 40.8% were more than 60 years old. The prevalence of anemia was 83.6%. The mean hemoglobin level was 9.7 ± 3 g/dL. Furthermore, 36.7% had acute myeloid leukemia (AML), 36.7% had chronic lymphocytic leukemia (CLL), 22.5% had acute lymphoblastic leukemia (ALL), while only 2% had chronic myeloid leukemia (CML) and 2% had non-Hodgkin lymphoma (NHL). The most common type of anemia was normocytic normochromic anemia (55.6%), followed by macrocytic hyperchromic anemia (24.4%). All patients diagnosed with AML, ALL, CML, or NHL had anemia at time of diagnosis. However, the prevalence of anemia among patients diagnosed with CLL was 55%.

Conclusions: Anemia is highly prevalent among patients with leukemia at time of diagnosis. Early identification and correction are crucial to improve QOL and reduce complications from chemotherapy.

查看原文本刊更多论文

沙特阿拉伯新诊断白血病患者贫血的患病率及特点

背景：白血病患者的贫血导致生活质量（QOL）差，化疗并发症风险增加。我们的目的是确定新诊断的急性和慢性白血病患者贫血的患病率和特征。方法：一项回顾性队列研究包括2019年至2023年在沙特阿拉伯塔伊夫市费萨尔国王医疗中心诊断为白血病的所有患者。结果：49例新诊断白血病患者中，男性占57%，60岁以上患者占40.8%。贫血患病率为83.6%。平均血红蛋白水平为9.7±3 g/dL。此外，36.7%为急性髓性白血病（AML）， 36.7%为慢性淋巴细胞白血病（CLL）， 22.5%为急性淋巴细胞白血病（ALL），而只有2%为慢性髓性白血病（CML）和2%为非霍奇金淋巴瘤（NHL）。最常见的贫血类型为正红细胞性正色贫血（55.6%），其次是大细胞性高色贫血（24.4%）。所有被诊断为AML、All、CML或NHL的患者在诊断时都有贫血。然而，在诊断为CLL的患者中，贫血的患病率为55%。结论：白血病患者诊断时贫血发生率高。早期发现和纠正是提高生活质量和减少化疗并发症的关键。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical laboratory 医学-医学实验技术

CiteScore

1.50

自引率

0.00%

发文量

494

审稿时长

3 months

期刊介绍： Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.