Giovana Solheid Gil, Gabriela Monteiro Barbosa Xavier, Caio Augusto de Almeida Canelas, Rafael Rodrigues Lima, Ana Paula Drummond Rodrigues, Jesuina Lamartine Nogueira Araújo, Marcele Fonseca Passos, Cecy Martins Silva
{"title":"Effect of copaiba oil-resin on dental sensitivity control and color change after bleaching: A randomized clinical trial.","authors":"Giovana Solheid Gil, Gabriela Monteiro Barbosa Xavier, Caio Augusto de Almeida Canelas, Rafael Rodrigues Lima, Ana Paula Drummond Rodrigues, Jesuina Lamartine Nogueira Araújo, Marcele Fonseca Passos, Cecy Martins Silva","doi":"10.1007/s00784-025-06375-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This randomized clinical trial evaluated a copaiba oil-based gel in controlling dental sensitivity (DS) and color change after dental bleaching.</p><p><strong>Materials and methods: </strong>Seventy-five volunteers were randomized into three groups (n = 25): GC (placebo gel - negative control); GKF2% (gel of 5% potassium nitrate and 2% sodium fluoride - positive control); and GCO (copaiba oil gel). Three bleaching sessions were performed using 35% hydrogen peroxide (HP 35%), with 7-day intervals. The desensitizing gels were applied for 10 min in each group. The DS was evaluated over 21 days using a visual analog scale (VAS). Color evaluation was done with a spectrophotometer before and after bleaching using the CIEDE2000. The DS was assessed between groups (Kruskal-Wallis test) and within groups (Friedman test). The color change was analyzed using one-way ANOVA and Tukey's test.</p><p><strong>Results: </strong>GCO and GKF2% showed the lowest sensitivity values, with no significant difference (p < 0.05). In the intragroup analysis, GCO and GKF2% showed no differences across the three whitening sessions (p = 0.974, p = 0.213, p = 0.143, respectively). Conversely, GC exhibited an increase in DS after the last session (p = 0.035). All groups showed color change, without statistically significant differences between the groups (p = 0.725).</p><p><strong>Conclusion: </strong>The copaiba gel reduced dental sensitivity after treatment with 35% hydrogen peroxide, without affecting the bleaching effectiveness.</p><p><strong>Clinical relevance: </strong>The topical application of the experimental copaiba oil gel was effective in reducing dental sensitivity after bleaching with 35% hydrogen peroxide.</p>","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":"29 6","pages":"296"},"PeriodicalIF":3.1000,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Oral Investigations","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00784-025-06375-5","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This randomized clinical trial evaluated a copaiba oil-based gel in controlling dental sensitivity (DS) and color change after dental bleaching.
Materials and methods: Seventy-five volunteers were randomized into three groups (n = 25): GC (placebo gel - negative control); GKF2% (gel of 5% potassium nitrate and 2% sodium fluoride - positive control); and GCO (copaiba oil gel). Three bleaching sessions were performed using 35% hydrogen peroxide (HP 35%), with 7-day intervals. The desensitizing gels were applied for 10 min in each group. The DS was evaluated over 21 days using a visual analog scale (VAS). Color evaluation was done with a spectrophotometer before and after bleaching using the CIEDE2000. The DS was assessed between groups (Kruskal-Wallis test) and within groups (Friedman test). The color change was analyzed using one-way ANOVA and Tukey's test.
Results: GCO and GKF2% showed the lowest sensitivity values, with no significant difference (p < 0.05). In the intragroup analysis, GCO and GKF2% showed no differences across the three whitening sessions (p = 0.974, p = 0.213, p = 0.143, respectively). Conversely, GC exhibited an increase in DS after the last session (p = 0.035). All groups showed color change, without statistically significant differences between the groups (p = 0.725).
Conclusion: The copaiba gel reduced dental sensitivity after treatment with 35% hydrogen peroxide, without affecting the bleaching effectiveness.
Clinical relevance: The topical application of the experimental copaiba oil gel was effective in reducing dental sensitivity after bleaching with 35% hydrogen peroxide.
期刊介绍:
The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.