Divergent synthetic studies towards bisabosqual A and fargenone B via an intramolecular S_N2 reaction.

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-05-12 DOI:10.1039/d5ob00655d

Chen Guo, Mao-Mei Zhu, Si-Ji Ze Lang, Ya-Wen Wang, Jian Xiao, Yu Peng

引用次数: 0

Abstract

A divergent approach has been developed towards the synthetic studies of bisabosqual A and fargenone B for the first time. The key oxygenated five- or seven-membered ring in [6-5-6] and [6-7-6] tricyclic cores of these two natural products could be constructed through a regioselective intramolecular S_N2 reaction from the common advanced intermediate 11.

查看原文本刊更多论文

通过分子内SN2反应合成双角鲨A和法根酮B的不同研究。

对双角鲨A和法基酮B的合成研究首次提出了不同的方法。这两种天然产物的[6-5-6]和[6-7-6]三环核心中的关键氧合五元或七元环可以由共同的高级中间体11通过区域选择性的分子内SN2反应构建。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.

Divergent synthetic studies towards bisabosqual A and fargenone B via an intramolecular SN2 reaction.

Abstract

Divergent synthetic studies towards bisabosqual A and fargenone B via an intramolecular S_N2 reaction.