Dual-mechanism detecting fluoride and tetracycline in food matrices using red-emitting carbon dots.

IF 5.6 1区化学 Q1 CHEMISTRY, ANALYTICAL

Talanta Pub Date : 2025-10-01 Epub Date: 2025-04-10 DOI:10.1016/j.talanta.2025.128126

Yumin Hao, Xiaole Wen, Xiaofang Zheng, Huiping Wang, Wenjuan Dong, Yang Liu, Shengmei Song, Shaomin Shuang, Yujing Guo, Chuan Dong, Xiaojuan Gong

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引用次数: 0

Abstract

Excessive exposure to fluoride and tetracycline can cause severe dental damage, including tetracycline-induced tooth discoloration and dental fluorosis. Herein, we introduce a dual-mechanism sensing strategy using red-emitting carbon dots (R-CDs) for the independent detection of fluoride and tetracycline. A key advantage of R-CDs as sensors is their ability to selectively identify both analytes through long-wavelength emission with a large Stokes shift. For fluoride detection, we developed a fluorescence-enhanced sensor based on R-CDs-Fe³⁺ via a competitive binding mechanism. Meanwhile, tetracycline detection was achieved using a fluorescence-quenching sensor leveraging static quenching and the internal filter effect (IFE). The successful quantification of fluoride and tetracycline in food matrices demonstrates the practical potential of R-CDs in food safety monitoring. Additionally, this study presents a novel framework for designing multi-target detection systems using a single type of carbon dots across different sensing mechanisms.

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利用红碳点双机制检测食品基质中的氟化物和四环素。

过量接触氟化物和四环素会造成严重的牙齿损伤，包括四环素引起的牙齿变色和氟斑牙。本文介绍了一种利用红碳点（R-CDs）进行氟化物和四环素独立检测的双机制传感策略。R-CDs作为传感器的一个关键优势是，它们能够通过具有大斯托克斯位移的长波发射选择性地识别两种分析物。对于氟化物检测，我们通过竞争结合机制开发了基于R-CDs-Fe3+的荧光增强传感器。同时，利用静态猝灭和内部过滤效应（IFE）的荧光猝灭传感器实现四环素检测。食品基质中氟化物和四环素的成功定量显示了r - cd在食品安全监测中的实际潜力。此外，本研究提出了一种新的框架，用于设计跨不同传感机制使用单一类型碳点的多目标检测系统。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Talanta 化学-分析化学

CiteScore

12.30

自引率

4.90%

发文量

861

审稿时长

29 days

期刊介绍： Talanta provides a forum for the publication of original research papers, short communications, and critical reviews in all branches of pure and applied analytical chemistry. Papers are evaluated based on established guidelines, including the fundamental nature of the study, scientific novelty, substantial improvement or advantage over existing technology or methods, and demonstrated analytical applicability. Original research papers on fundamental studies, and on novel sensor and instrumentation developments, are encouraged. Novel or improved applications in areas such as clinical and biological chemistry, environmental analysis, geochemistry, materials science and engineering, and analytical platforms for omics development are welcome. Analytical performance of methods should be determined, including interference and matrix effects, and methods should be validated by comparison with a standard method, or analysis of a certified reference material. Simple spiking recoveries may not be sufficient. The developed method should especially comprise information on selectivity, sensitivity, detection limits, accuracy, and reliability. However, applying official validation or robustness studies to a routine method or technique does not necessarily constitute novelty. Proper statistical treatment of the data should be provided. Relevant literature should be cited, including related publications by the authors, and authors should discuss how their proposed methodology compares with previously reported methods.