A new mortality score in preterm infants: the vasoactive inotropic score.

IF 2 3区医学 Q2 PEDIATRICS

BMC Pediatrics Pub Date : 2025-04-23 DOI:10.1186/s12887-025-05638-0

Elif Özalkaya, İlter Arifoğlu, Emre Yarış, Sevilay Topcuoğlu, Selim Sancak, Emre Dinçer, Özge Yatır Alkan, Güner Karatekin

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引用次数: 0

Abstract

Objectives: The aim of this study is to evaluate the predictive value of the vasoactive inotropic score (VIS) for mortality in extremely low birth weight (ELBW) preterm infants and to compare this value with the well-known Clinical Risk Index for Babies-II (CRIB-II) score.

Methods: This study was designed as a retrospective study. A total of 280 preterm infants weighing under 1000 g who were admitted to the neonatal intensive care unit over a five-year period were included in the study. For each patient, a CRIB-II score and VIS were calculated, and their ability to predict mortality was compared. To predict and compare the accuracy of the scoring systems, Receiver Operating Characteristic (ROC) analysis was used, and the area under the curve (AUC) was calculated.

Results: In infants who died within the first 28 days after birth, the CRIB-II score (p < 0.001) and VISmax (p < 0.001) were higher compared with those who survived. The AUCs for the CRIB-II score and VIS in predicting mortality were 0.86/0.81, with cut-offs of > 12/ > 5, sensitivities of 79/70, specificities of 82/87, positive predictive values (PPVs) of 81/85, and negative predictive values (NPVs) of 80/75. There were no statistically significant differences between the AUC values of the CRIB-II score and VIS variables (p = 0.160).

Conclusion: The VIS can predict mortality in ELBW preterm infants as accurately as the CRIB-II score can.

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一种新的早产儿死亡率评分：血管活性性肌力评分。

目的：本研究的目的是评估血管活性性肌力评分（VIS）对极低出生体重（ELBW）早产儿死亡率的预测价值，并将其与众所周知的婴儿临床风险指数- ii （CRIB-II）评分进行比较。方法：本研究采用回顾性研究。在这项研究中，共有280名体重在1000克以下的早产儿在5年内被新生儿重症监护病房收治。对每位患者计算CRIB-II评分和VIS，并比较其预测死亡率的能力。为了预测和比较评分系统的准确性，采用受试者工作特征（ROC）分析，并计算曲线下面积（AUC）。结果：出生后28天内死亡的婴儿，CRIB-II评分（p 12/ bbb50），敏感性为79/70，特异性为82/87，阳性预测值（ppv）为81/85，阴性预测值（npv）为80/75。CRIB-II评分与VIS变量的AUC值差异无统计学意义（p = 0.160）。结论：VIS可与CRIB-II评分一样准确预测ELBW早产儿的死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Pediatrics PEDIATRICS-

CiteScore

3.70

自引率

4.20%

发文量

683

审稿时长

3-8 weeks

期刊介绍： BMC Pediatrics is an open access journal publishing peer-reviewed research articles in all aspects of health care in neonates, children and adolescents, as well as related molecular genetics, pathophysiology, and epidemiology.