Under the weather: an epidemic thunderstorm asthma event in Leicester, June 2023.

IF 3.4 3区 医学 Q1 RESPIRATORY SYSTEM
Sarah Diver, Fiona Symon, Jack Satchwell, Heather Lipscombe, Ruth H Green, Gerrit Woltmann, Damian Roland, Erol A Gaillard, Anna Hansell, Chris Brightling, Leah Cuthbertson
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引用次数: 0

Abstract

In the context of climate change and increasing global populations, thunderstorm asthma may become a greater threat at both individual and population levels. The unpredictable nature of epidemic thunderstorm asthma events makes them challenging to study; however, they can have devastating consequences. Novel approaches are required to characterise the mechanisms driving these events to allow researchers and other stakeholders to understand who is at risk and when. This will support the development of interventions that protect patients and healthcare services. In this commentary, we provide an overview of thunderstorm asthma and briefly describe an epidemic affecting Leicester, UK in June 2023. Our analysis highlights Cladosporium spores as a key player in mediating UK thunderstorm asthma. Low levels of background treatment in adults and an increase in emergency assessments but not hospitalisations in children suggest that epidemics could be prevented by improving awareness and ensuring access to standard inhaled therapies. Finally, we consider future risk and suggest research priorities with an ultimate goal of minimising the adverse impact related to thunderstorm asthma going forward.

天气下:2023年6月莱斯特的流行病雷暴哮喘事件。
在气候变化和全球人口增加的背景下,雷暴哮喘可能在个人和群体层面上成为更大的威胁。流行性雷暴哮喘事件的不可预测性使其研究具有挑战性;然而,它们可能带来毁灭性的后果。需要新的方法来描述驱动这些事件的机制,以使研究人员和其他利益相关者了解谁处于危险之中以及何时处于危险之中。这将支持制定保护患者和保健服务的干预措施。在这篇评论中,我们提供了雷暴哮喘的概述,并简要描述了2023年6月影响英国莱斯特的流行病。我们的分析强调枝孢子是介导英国雷暴哮喘的关键角色。成人背景治疗水平低,儿童紧急评估增加,但没有住院治疗,这表明可以通过提高认识和确保获得标准吸入疗法来预防流行病。最后,我们考虑了未来的风险,并提出了研究重点,最终目标是最大限度地减少与雷暴哮喘相关的不利影响。
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来源期刊
BMJ Open Respiratory Research
BMJ Open Respiratory Research RESPIRATORY SYSTEM-
CiteScore
6.60
自引率
2.40%
发文量
95
审稿时长
12 weeks
期刊介绍: BMJ Open Respiratory Research is a peer-reviewed, open access journal publishing respiratory and critical care medicine. It is the sister journal to Thorax and co-owned by the British Thoracic Society and BMJ. The journal focuses on robustness of methodology and scientific rigour with less emphasis on novelty or perceived impact. BMJ Open Respiratory Research operates a rapid review process, with continuous publication online, ensuring timely, up-to-date research is available worldwide. The journal publishes review articles and all research study types: Basic science including laboratory based experiments and animal models, Pilot studies or proof of concept, Observational studies, Study protocols, Registries, Clinical trials from phase I to multicentre randomised clinical trials, Systematic reviews and meta-analyses.
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