Structure and Functions of NDR1/HIN1-Like (NHL) Proteins in Plant Development and Response to Environmental Stresses.

IF 6 1区生物学 Q1 PLANT SCIENCES

Plant, Cell & Environment Pub Date : 2025-04-21 DOI:10.1111/pce.15569

Victoria Amato, Shantel Mahalath, Liyuan Zhang, Paul J Rushton, Qingxi J Shen

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引用次数: 0

Abstract

The NON-RACE-SPECIFIC DISEASE RESISTANCE 1/harpin-induced 1-LIKE (NHL) gene family plays pivotal roles, including pathogen resistance, abiotic stress tolerance, and developmental regulation, underscoring their functional versatility in developmental and physiological processes of plants. NHL proteins often localize to the plasma membrane and contain conserved motifs, including the LEA2 and transmembrane domains, enabling dynamic interactions with signalling molecules and transcription factors. The ability of NHL proteins to dimerize and oligomerize further enhances their regulatory potential in signalling pathways. This review explores the structural and functional diversity of NHL proteins including their localizations, interacting proteins, and responses to abiotic and biotic stresses, ion transportation, seed germination, and responses to phytohormones. Future research integrating phylogenetics, and advanced tools including artificial intelligence will unlock the full potential of this gene family for breeding climate-resilient crops and agricultural sustainability.

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NDR1/ hin1样蛋白（NHL）在植物发育和环境胁迫响应中的结构和功能

NON-RACE-SPECIFIC DISEASE RESISTANCE 1/harpin-induced 1- like （NHL）基因家族在植物的抗病、抗非生物胁迫和发育调控等方面起着关键作用，在植物的发育和生理过程中具有多功能性。NHL蛋白通常定位于质膜，并含有保守的基序，包括LEA2和跨膜结构域，能够与信号分子和转录因子进行动态相互作用。NHL蛋白二聚化和寡聚化的能力进一步增强了它们在信号通路中的调控潜力。本文综述了NHL蛋白的结构和功能多样性，包括它们的定位、相互作用蛋白、对非生物和生物胁迫的反应、离子运输、种子萌发和对植物激素的反应。未来的研究将整合系统发育和包括人工智能在内的先进工具，将释放该基因家族的全部潜力，以培育适应气候变化的作物和农业可持续性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Plant, Cell & Environment 生物-植物科学

CiteScore

13.30

自引率

4.10%

发文量

253

审稿时长

1.8 months

期刊介绍： Plant, Cell & Environment is a premier plant science journal, offering valuable insights into plant responses to their environment. Committed to publishing high-quality theoretical and experimental research, the journal covers a broad spectrum of factors, spanning from molecular to community levels. Researchers exploring various aspects of plant biology, physiology, and ecology contribute to the journal's comprehensive understanding of plant-environment interactions.