High-Viability Circulating Tumor Cells Sorting From Whole Blood at Single Cell Level Using Laser-Induced Forward Transfer-Assisted Microfiltration (Adv. Sci. 18/2025)

IF 14.3 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-05-15 DOI:10.1002/advs.202570130

Qingmei Xu, Yuntong Wang, Songtao Dou, Yang Xu, Zhenhe Xu, Han Xu, Yi Zhang, Yanming Xia, Ying Xue, Hang Li, Xiao Ma, Kunlong Zhang, Huan Wang, Fengzhou Ma, Qi Wang, Bei Li, Wei Wang

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引用次数: 0

Abstract

Integrated Single Rare Cell Sorting System

Circulating tumor cells (CTCs) represent a rare and heterogeneous population of cancer cells, serving as critical biomarkers for metastasis monitoring and personalized medicine. However, efficiently isolating single, high-viability CTCs from complex blood environments remains a significant challenge. In article 2414195, Wei Wang, Bei Li, Qi Wang, and co-workers present a laser-induced forward transfer-assisted microfiltration system for the high-efficiency enrichment and precise retrieval of single CTCs from whole blood. This innovative platform provides a robust and versatile tool for advancing single-CTC research.

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激光诱导前向转移辅助微滤在单细胞水平上从全血中分选高活力循环肿瘤细胞（Sci. 18/2025）

循环肿瘤细胞（CTCs）代表了一种罕见且异质性的癌细胞群体，是转移监测和个性化医疗的关键生物标志物。然而，从复杂的血液环境中有效地分离单一的、高活力的ctc仍然是一个重大挑战。在文章2414195中，王伟、李蓓、王琦等人提出了一种激光诱导正向转移辅助微滤系统，用于全血中单个ctc的高效富集和精确提取。这个创新的平台为推进单ctc研究提供了一个强大而通用的工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.