Chaimae Abourak, Aya Laridi, Ouafaa Chahboune, Siham Oukassem, Asmae Guennouni, Soukaina Bahha, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad
{"title":"Mammary Paget’s disease in a young woman: A rare occurrence","authors":"Chaimae Abourak, Aya Laridi, Ouafaa Chahboune, Siham Oukassem, Asmae Guennouni, Soukaina Bahha, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad","doi":"10.1016/j.radcr.2025.04.062","DOIUrl":null,"url":null,"abstract":"<div><div>Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"20 8","pages":"Pages 3733-3737"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1930043325003449","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.
期刊介绍:
The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.