Iron catalyzed N-arylation of 7-azaindole with aryl iodides

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2025-05-05 DOI:10.1080/00397911.2025.2496968

Yong-Chua Teo (Conceptualization Funding acquisition Supervision Writing – original draft Writing – review & editing) , Ying-Rui Tan (Investigation Methodology) , Wei-Zhi Ang (Investigation Methodology) , Anthia Shun-Ai Teo (Investigation Methodology)

引用次数: 0

Abstract

A simple and efficient ligand-assisted iron-catalyzed system for the C-N coupling of 7-azaindole with aryl iodides was developed using water as the sole solvent. Under the optimum conditions, the N-arylated products were obtained in good yields up to 96%.

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铁催化7-叠氮吲哚与芳基碘化物的n -芳化反应

以水为唯一溶剂，建立了一种简单高效的配体辅助铁催化体系，用于7-叠氮酚与芳基碘化物的C-N偶联反应。在此条件下，n -芳基化产物的收率可达96%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.