A meta-analysis to identify factors affecting solid and liquid digesta mean retention time in equines

IF 1.3 3区 农林科学 Q2 VETERINARY SCIENCES
K. Papadakis , E.M. Leishman , P.S. Darani , S. Cieslar , J.L. Ellis
{"title":"A meta-analysis to identify factors affecting solid and liquid digesta mean retention time in equines","authors":"K. Papadakis ,&nbsp;E.M. Leishman ,&nbsp;P.S. Darani ,&nbsp;S. Cieslar ,&nbsp;J.L. Ellis","doi":"10.1016/j.jevs.2025.105434","DOIUrl":null,"url":null,"abstract":"<div><div>How quickly feed passes through the equine gastrointestinal tract (GIT) or specific compartments of the GIT is an important determinant of nutrient digestion and absorption. Typically, this process is quantified by measuring mean retention time (MRT), or the average number of hours required to pass a labeled feedstuff/digesta fraction. While determinants of MRT have been studied extensively in other species resulting in empirical equations, equine data lack such quantitative summaries. The variability in experimental diets and subjects (i.e., sex, breed, age) across equine studies makes qualitative comparisons difficult. Therefore, the objective of this study was to conduct a meta-analysis across available MRT data from published equine studies to determine factors (e.g., dietary, physiological, management) that affect equine MRT and to develop predictive/descriptive equations for MRT in equines. Such equations would be useful in the prediction of feedstuff or nutrient digestibility, as well as the development of models of nutrient utilization. A systematic literature search was conducted which yielded 24 papers (144 mean observations of total-tract MRT, for solid and liquid digesta) that met the criteria for inclusion (must report MRT, and have a change in diet given). Information extracted from the papers included (as available) body weight, classification as horse or pony, age, dry matter intake, forage particle size, feed ingredients, diet nutrient composition, forage to concentrate ratio, and so on. A linear mixed model analysis treating study as a random effect was conducted to identify significant driving variables and quantify their effects on MRT across the published literature. Model fit was evaluated using visual plots, root Mean Square Prediction Error (rMSPE), and the Concordance Correlation Coefficient (CCC) statistic. For total-tract liquid digesta MRT (h), it was found that whether the equine was a horse or pony, the DMI (kg/d) and ADF (g/kg DM) content of the diet yielded the best model predictions (raw CCC: 0.712, raw rMSPE: 22.0%, conditioned CCC: 0.900, conditioned rMSPE 12.9%). For the solid digesta MRT (h) models, whether it was a horse or pony, the DMI (kg/d), the roughage percent of the diet, and the NDF (g/kg DM) content of the diet yielded the best model predictions (raw CCC: 0.469, raw rMSPE: 18.6%, conditioned CCC: 0.885, conditioned rMSPE 9.1%). These models confirm existing knowledge while developing tools to predict MRT in horses going forward, not only advancing the field of quantitative equine nutrition but also enhancing our ability to predict nutrient digestibility in horses.</div></div>","PeriodicalId":15798,"journal":{"name":"Journal of Equine Veterinary Science","volume":"148 ","pages":"Article 105434"},"PeriodicalIF":1.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Equine Veterinary Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0737080625000929","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

How quickly feed passes through the equine gastrointestinal tract (GIT) or specific compartments of the GIT is an important determinant of nutrient digestion and absorption. Typically, this process is quantified by measuring mean retention time (MRT), or the average number of hours required to pass a labeled feedstuff/digesta fraction. While determinants of MRT have been studied extensively in other species resulting in empirical equations, equine data lack such quantitative summaries. The variability in experimental diets and subjects (i.e., sex, breed, age) across equine studies makes qualitative comparisons difficult. Therefore, the objective of this study was to conduct a meta-analysis across available MRT data from published equine studies to determine factors (e.g., dietary, physiological, management) that affect equine MRT and to develop predictive/descriptive equations for MRT in equines. Such equations would be useful in the prediction of feedstuff or nutrient digestibility, as well as the development of models of nutrient utilization. A systematic literature search was conducted which yielded 24 papers (144 mean observations of total-tract MRT, for solid and liquid digesta) that met the criteria for inclusion (must report MRT, and have a change in diet given). Information extracted from the papers included (as available) body weight, classification as horse or pony, age, dry matter intake, forage particle size, feed ingredients, diet nutrient composition, forage to concentrate ratio, and so on. A linear mixed model analysis treating study as a random effect was conducted to identify significant driving variables and quantify their effects on MRT across the published literature. Model fit was evaluated using visual plots, root Mean Square Prediction Error (rMSPE), and the Concordance Correlation Coefficient (CCC) statistic. For total-tract liquid digesta MRT (h), it was found that whether the equine was a horse or pony, the DMI (kg/d) and ADF (g/kg DM) content of the diet yielded the best model predictions (raw CCC: 0.712, raw rMSPE: 22.0%, conditioned CCC: 0.900, conditioned rMSPE 12.9%). For the solid digesta MRT (h) models, whether it was a horse or pony, the DMI (kg/d), the roughage percent of the diet, and the NDF (g/kg DM) content of the diet yielded the best model predictions (raw CCC: 0.469, raw rMSPE: 18.6%, conditioned CCC: 0.885, conditioned rMSPE 9.1%). These models confirm existing knowledge while developing tools to predict MRT in horses going forward, not only advancing the field of quantitative equine nutrition but also enhancing our ability to predict nutrient digestibility in horses.
一项荟萃分析,以确定影响马的固体和液体消化平均滞留时间的因素
饲料通过马胃肠道(GIT)或胃肠道特定区室的速度是营养物质消化和吸收的重要决定因素。通常,该过程通过测量平均滞留时间(MRT)或通过标记饲料/消化物部分所需的平均小时数来量化。虽然MRT的决定因素已经在其他物种中进行了广泛的研究,导致经验方程,但马的数据缺乏这样的定量总结。在马研究中,实验饮食和受试者(即性别、品种、年龄)的可变性使得定性比较变得困难。因此,本研究的目的是对已发表的马研究中可用的MRT数据进行荟萃分析,以确定影响马MRT的因素(如饮食、生理、管理),并建立马MRT的预测/描述性方程。该方程可用于预测饲料或营养物质的消化率,并可用于建立营养物质利用模型。进行了系统的文献检索,得出24篇符合纳入标准的论文(144篇平均观察全道MRT,固体和液体消化)(必须报告MRT,并改变饮食)。从论文中提取的信息包括(尽可能)体重、马或马的分类、年龄、干物质采食量、饲料粒度、饲料成分、日粮营养成分、料精比等。将研究视为随机效应的线性混合模型分析进行了识别重要驱动变量并量化其对已发表文献中MRT的影响的研究。采用目视图、均方根预测误差(rMSPE)和一致性相关系数(CCC)统计量评估模型拟合。对于全路液体消化MRT (h),无论马是马还是小马,日粮的DMI (kg/d)和ADF (g/kg DM)含量均产生最佳模型预测(原始CCC: 0.712,原始rMSPE: 22.0%,条件CCC: 0.900,条件rMSPE 12.9%)。对于固体食糜MRT (h)模型,无论是马还是小马,DMI (kg/d)、日粮粗饲料百分比和日粮NDF (g/kg DM)含量都产生了最好的模型预测(原始CCC: 0.469,原始rMSPE: 18.6%,条件CCC: 0.885,条件rMSPE 9.1%)。这些模型证实了现有的知识,同时开发了预测马的MRT的工具,不仅推进了定量马营养领域,而且增强了我们预测马的营养消化率的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Equine Veterinary Science
Journal of Equine Veterinary Science 农林科学-兽医学
CiteScore
2.70
自引率
7.70%
发文量
249
审稿时长
77 days
期刊介绍: Journal of Equine Veterinary Science (JEVS) is an international publication designed for the practicing equine veterinarian, equine researcher, and other equine health care specialist. Published monthly, each issue of JEVS includes original research, reviews, case reports, short communications, and clinical techniques from leaders in the equine veterinary field, covering such topics as laminitis, reproduction, infectious disease, parasitology, behavior, podology, internal medicine, surgery and nutrition.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信