RBRL co-opts NINJA for plant defense

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2025-05-14 DOI:10.1016/j.chom.2025.04.004

Fangfang Ma, Zhilong Bao

引用次数: 0

Abstract

Antiviral defense requires signal transmission that connects the perception of viral infection to activation of plant immunity. Findings in Nature by Huang et al. describe key players whereby RING1-IBR-RING2-type ubiquitin ligase (RBRL) recognizes viral coat proteins to release NINJA3-mediated suppression of jasmonate signaling and initiate broad-spectrum antiviral responses in rice.

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RBRL采用NINJA进行植物防御

抗病毒防御需要信号传输，将病毒感染的感知与植物免疫的激活联系起来。Huang等人在Nature杂志上的研究结果描述了ring1 - ibr - ring2型泛素连接酶（RBRL）识别病毒外壳蛋白以释放ninja3介导的茉莉酸信号抑制并在水稻中启动广谱抗病毒反应的关键参与者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.