The Novel HLA-E*01:152 Allele Identified in African Populations Using Next-Generation Sequencing

IF 5.9 4区医学 Q2 CELL BIOLOGY

HLA Pub Date : 2025-05-13 DOI:10.1111/tan.70247

Nitalia Naidoo, Tiza L. Ng'uni, Uvedhna Padia, Alabi W. Banjoko, Zaza M. Ndhlovu

引用次数: 0

Abstract

E*01:152 differs from E*01:03:05:01 by a non-synonymous A>G substitution at gDNA position 958 (exon 3).

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新一代测序在非洲人群中鉴定出新的HLA-E*01:152等位基因

E*01:152与E*01:03:05:01的不同之处在于gDNA位置958（外显子3）有一个非同义的a >；G取代。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.