Self-reported motoric cognitive risk syndrome predicts long-term mortality in older adults

IF 4 3区医学 Q1 GERIATRICS & GERONTOLOGY

Journal of Nutrition Health & Aging Pub Date : 2025-05-14 DOI:10.1016/j.jnha.2025.100578

Yiwen Xing , Li Zhang , Pan Liu , Yiming Pan , Zhe Tang , Lina Ma

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引用次数: 0

Abstract

Objectives

Motoric cognitive risk syndrome (MCR) is a pre-dementia syndrome characterized by slow gait and subjective cognitive decline, increasing the risk of adverse clinical events such as dementia and falls in older adults. However, whether self-reported MCR (sMCR) predicts long-term mortality in Chinese older adults remains unknown. This study aimed to explore the role of sMCR in 8-year mortality in community-dwelling older adults.

Design

Longitudinal cohort study.

Setting

Data were sourced from the Beijing Longitudinal Study of Aging.

Participants

A total of 1,683 community-dwelling individuals aged 65 years and older who were free from disability and dementia at baseline were included.

Measurements

sMCR was defined based on the presence of subjective cognitive decline and self-reported slow gait. Mortality data were tracked over the 8-year follow-up period. Cox regression models were used to analyze the association between sMCR and 8-year mortality.

Results

A total of 113 (6.71%) community-dwelling individuals had sMCR. sMCR was associated with female sex, older age, no spouse, living in rural areas, low education level, low monthly income, no work, no tea intake, poor sleep quality, inactivity, poor physical performance, chronic diseases, and frailty. Participants with sMCR had a higher 8-year mortality compared to those without (70.80% vs. 34.52%). Cox regression analysis showed that sMCR predicted 8-year mortality (hazard ratio [HR] = 2.859, 95% confidence interval [CI] 2.260–3.619). This association remained significant even after adjusting for sex, age, area, education level, marital status, chronic diseases, and lifestyle factors (HR = 1.540, 95% CI 1.169–2.028).

Conclusions

sMCR is a predictor of 8-year mortality in Chinese community-dwelling older adults, which highlights the importance of early identification and intervention for sMCR to reduce adverse clinical outcomes in the aging population.

查看原文本刊更多论文

自我报告的运动认知风险综合征预测老年人的长期死亡率

运动认知风险综合征（MCR）是一种以步态缓慢和主观认知能力下降为特征的痴呆前期综合征，增加了老年人痴呆和跌倒等不良临床事件的风险。然而，自我报告的MCR （sMCR）是否能预测中国老年人的长期死亡率仍然未知。本研究旨在探讨sMCR在社区居住老年人8年死亡率中的作用。设计纵向队列研究。数据来源于北京老龄化纵向研究。参与者共包括1683名65岁及以上的社区居民，他们在基线时没有残疾和痴呆。测量方法：smcr是根据主观认知能力下降和自我报告的步态缓慢来定义的。死亡率数据在8年的随访期间被追踪。采用Cox回归模型分析sMCR与8年死亡率之间的关系。结果共有113人（6.71%）患有sMCR。sMCR与女性、年龄较大、无配偶、生活在农村、受教育程度低、月收入低、没有工作、不喝茶、睡眠质量差、不活动、身体机能差、慢性病和体弱多病有关。sMCR患者的8年死亡率高于无sMCR患者（70.80% vs. 34.52%）。Cox回归分析显示，sMCR预测8年死亡率（风险比[HR] = 2.859, 95%可信区间[CI] 2.260 ~ 3.619）。即使在调整了性别、年龄、地区、教育程度、婚姻状况、慢性病和生活方式等因素后，这种相关性仍然显著（HR = 1.540, 95% CI 1.169-2.028）。结论sMCR是中国社区老年人8年死亡率的预测因子，这突出了早期识别和干预sMCR对减少老年人群不良临床结局的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nutrition Health & Aging 医学-老年医学

CiteScore

7.80

自引率

3.40%

发文量

136

审稿时长

4-8 weeks

期刊介绍： There is increasing scientific and clinical interest in the interactions of nutrition and health as part of the aging process. This interest is due to the important role that nutrition plays throughout the life span. This role affects the growth and development of the body during childhood, affects the risk of acute and chronic diseases, the maintenance of physiological processes and the biological process of aging. A major aim of "The Journal of Nutrition, Health & Aging" is to contribute to the improvement of knowledge regarding the relationships between nutrition and the aging process from birth to old age.